The S2G Podcast

Hosted by S2G Investments

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Oct 2026

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This is the S2G Podcast, where we talk to business leaders, investors, policymakers, and thought leaders who have a transformative vision for the future. We’ll explore how their experiences and perspectives offer lessons into scaling the food, agriculture, oceans, and energy transitions.

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November 9, 202648 min

After the Midterms: The Politics of Affordability

Last week’s elections produced one of the biggest midterm swings in decades. Many of the issues behind that shift, from rising food and energy costs to tariffs and the war in Iran, land squarely in the sectors S2G invests in. In this episode, S2G’s Sanjeev Krishnan sits down with Grant Leslie, S2G’s Operating Partner for Government & Policy, and Carlos Odio, co-founder of Equis Research, to unpack what happened and what comes next. Carlos explains what produced the swing, and why data centers became a political issue on both sides of the aisle. Grant describes a new class of pragmatic lawmakers under pressure to deliver on affordability, and why farm states that rarely vote on pocketbook issues did so this time. They close with advice for founders and investors on why politics is no longer something capital can ignore. Chapters: 03:07 – A historic midterm 11:37 – What happens next in Washington 14:16 – A new class of pragmatic, heterodox candidates 17:38 – What the results mean for energy, food and ag 20:57 – How data centers became a political flashpoint 28:11 – Why farm country voted with its wallet 32:01 – Immigration, farm labor and the Trump White House’s factions 34:35 – Advice for founders: lead with affordability 36:24 – What 2026 tells us about 2028 41:18 – Why investors can’t afford to ignore politics This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

November 5, 2026Episode 2544 min

Closing the Ocean Data Gap with Apeiron Labs

In 2022, S2G helped found Apeiron Labs around one question: what would it take to cut the cost of collecting ocean data by a factor of 100, or even 1,000? The answer turned out to be low-cost underwater gliders combined with software that manages the network and processes measurements for customers. These vehicles are dual-use by design, and as demand for security rises, new investors and buyers are increasingly interested in technology that also improves weather forecasting, climate monitoring and our understanding of the ocean. In this episode, S2G’s Sanjeev Krishnan sits down with Apeiron co-founder Ravi Pappu and CEO Rob Rainhart to talk about how far the company has come, from a PowerPoint slide to thousands of hours of operation at sea. Ravi and Rob share how advances in cars, drones, and satellites helped them solve a tough systems engineering problem, and why the cost of watching an entire hurricane season in the Gulf of Mexico could soon be a rounding error. They also explain how steady, long-term ocean measurements could become some of the most valuable inputs to AI forecasting models, and why Ravi believes the company is one large manufacturing run away from delivering that data at scale. Chapters: 00:02:01 – Ravi and Rob's backgrounds 00:06:08 – The Ocean as a Global Blind Spot 00:10:16 – Validating the Low-Cost Sensing Model 00:14:51 – Lessons from the Aerial Drone Industry 00:19:14 – The Shift Toward Undersea Conflict 00:22:57 – Rebuilding Ocean Mapping and Navigation 00:26:46 – Commercial Applications in Energy, Shipping, and Insurance 00:30:47 – Engineering for Scale and Affordability 00:34:44 – The Role of AI in Ocean Intelligence 00:39:02 – The Future of Global Ocean Monitoring This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

October 29, 2026Episode 2421 min

Ocean Intelligence: Where Climate and Security Converge

For years, S2G has backed ocean monitoring for its impact on climate, fisheries, and ocean health, but rising geopolitical tensions have made it a national security priority too, and investment is following. The same technology that improves weather forecasts, tracks climate change, spots illegal fishing and follows whale migrations can also protect undersea cables, monitor shipping lanes and support defense. That dual use is what’s bringing new funding into the space. In this episode, S2G’s Sanjeev Krishnan and Kate Danaher join Tonya Bakritzes to talk about why these worlds are converging, and how the government has long been the first big customer for new technology, from GPS to semiconductors. They also take on the tough questions, including the risks of building a business on government contracts and how data collected for security could be put to work for the public good. The conversation sets the stage for next week’s episode with Apeiron Labs, whose low-cost underwater sensing vehicles serve both defense and climate-related use cases. 00:40: From Ocean Health to National Security 04:22: Why Government Is Often the First Customer 06:35: Why Ocean Monitoring Matters Now 09:25: How Ocean Warming Raises the Stakes 10:40: The Hard Questions of Dual Use Technologies 14:04: Putting Security Data to Public Use 16:15: Commercial Uses Beyond Government 17:47: Looking Ahead to the Next Decade This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

October 15, 2026Episode 2337 min

Who Holds the Risk in AI Infrastructure?

Capital is flowing into AI infrastructure at an unprecedented scale, but investors are not sharing risk equally. In both chips and data center financing, lenders generally favor amortizing structures that fully repay debt during the initial lease term. As a result, equity investors bear the residual value risk of the underlying assets, including both facilities and hardware. This dynamic reflects a core element of S2G’s Age of Adaptation thesis: the evolving cost and pricing of capital. Karen Fang, Global Head of Infrastructure & Sustainable Finance and Co-Head of the Global Capital Solutions at Bank of America, has spent 28 years in finance. She says nothing compares to the size of the deals she's working on now, and the cost of financing these projects has risen over the last year due to higher rates and wider spreads. In this episode, she and Sanjeev Krishnan discuss how different risk horizons can shape the way debt and equity investors price data center projects, what happens when chipmakers no longer guarantee the residual value of their chips, and why comparisons to the dot-com crash miss the mark. She also explains why solar and batteries still make up most of the new power capacity added to the U.S. grid. And she walks through a $16 billion data center campus in Michigan, financed through a structure her team designed, that uses existing grid capacity alongside battery storage, rather than relying on new power generation. If you invest in or finance real assets, this episode offers a useful look at how someone close to these deals thinks about risks the market is still learning to price. Chapters: 02:04 – Karen’s path from China to Tokyo to Wall Street 04:44 – Starting a finance career in the middle of the 1998 crisis 07:23 – The big trends reshaping investing, and why inflation may stick around 11:18 – Why the AI boom is nothing like the dot-com era 13:01 – Are we actually building too few data centers? 14:42 – How higher interest rates are raising the cost of AI projects 19:04 – Easing equipment shortages and the case for industrial policy 22:22 – Who really carries the risk on data centers and chips 28:41 – Why AI demand is fueling a solar and battery buildout 32:27 – Winning community support, and what’s coming next This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

October 1, 2026Episode 2239 min

Rebuilding American Agriculture Around Profit Instead of Yield

American agriculture has never been more productive, yet the system supporting it has become increasingly fragile. Farmers can produce extraordinary yields and still struggle to generate durable profits, while rising costs, concentrated markets, dependence on government support, aging farm ownership, input vulnerabilities, and intensifying global competition expose structural weaknesses that higher yields alone cannot solve. That is the central argument of Building the Missing Market: A National Strategy for American Agriculture , a new S2G report by Grant Leslie and Aaron Rudberg. The report calls for a fundamental shift in how American agriculture measures success, from yield per acre to risk adjusted profit per acre, meaning how much a farmer actually keeps from each acre and how reliably they keep it once costs and risks are accounted for. But changing the measure is only the beginning. Farmers who want to grow something different often lack the market around them: a committed buyer, a fair price, the financing and infrastructure to make the transition viable, and access to the innovation needed to manage it successfully. In this episode, report co-authors Aaron Rudberg and Grant Leslie are joined by Al Tank, an Iowa farmer, entrepreneur, and agriculture and trade policy expert. They discuss why the current farm bill may provide farmers with needed short-term certainty without addressing the underlying structural problems, why agriculture belongs in the same national security conversation as semiconductors and critical minerals, and why innovation, capital, policy, and market demand have to move together. The conversation ultimately asks what it would take to build a different system over the next decade, one in which a farmer who wants to grow something different has a real buyer, a fair price, and financing that allows them to make the transition without betting the farm. Chapters: 05:10 – Why This Report, and Why Now 08:08 – Shifting the Goal from Higher Yield to Higher Profits 11:03 – Who Moves First: Farmers or Buyers? 14:24 – A Dairy Success Story and Food as National Security 16:32 – Why the Current Farm Bill Falls Short 20:34 – How Farm Payments Discourage Change 24:59 – The 10-Year Plan in Three Phases 29:09 – Getting New Farm Technology to Market Faster 34:47 – What Success Looks Like in 10 Years This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

September 17, 2026Episode 2135 min

Rethinking Energy Security and What the World Got Wrong on Hormuz

Omran Al-Kuwari has been counting: September 16th marks 200 days since the Strait of Hormuz was closed, and there's still no fallback plan. As he puts it, a small regional airport might have more built-in redundancy than the Strait that feeds much of the world's energy. Omran, whose career in gas dates back to 1999, joins S2G's Sanjeev Krishnan and Frédéric Michel, the former chief strategy and communications advisor to Emmanuel Macron, to argue that Hormuz was never a regional problem. It's global critical infrastructure, and the risk reaches well past oil and gas into fertilizer, food prices, and even the helium hospitals need for MRI machines. Oil had its wake-up call in 1973 and built strategic stocks in response. LNG is having its wake-up call now. Omran explains why the weak points sit in the gaps between institutions, why we've built an architecture that keeps producing crises, and why the fix comes down to redundancy, governance, and deciding who pays for it. The conversation closes with a reframe: energy transitions don't swap one fuel for another, they stack new systems on old ones, and those systems now have to be built for a more volatile, fragmented world. Chapters: 01:52 Why Gulf energy is a global issue 06:12 What the headlines miss about Hormuz 08:09 Why global institutions haven't kept up 12:17 Who pays for backup supply? 15:49 How China weathered the shock 19:28 Gas prices, exports, and AI demand 23:46 How Qatar is bouncing back 29:41 Building a more resilient energy system This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

September 10, 2026Episode 2031 min

Energy Empire: The Nurse Who Built a $400 Million Generator Company

Concerts, construction sites, and data centers waiting on the grid all run on temporary power. That means a generator big enough for the rare occasions the site needs full power, burning through unnecessary fuel when the load is a fraction of what it can handle. ANA's system lets a battery carry the load and runs the engine only to recharge it, cutting fuel use for temporary power needs by as much as 80%. This week, we're featuring an episode from our friends at the Energy Empire podcast where hosts Jigar Shah and Jamie Nolan sit down with Alicia Waineo, Co-founder and CFO of ANA, one of our portfolio companies. They discuss how Alicia went from being a registered nurse to running a business doing roughly $400 million a year, why they kept the diesel engine when everyone else was trying to kill it, and how they funded the whole thing on $700,000 of their own money plus one outside check. Before we hand it over, S2G's Gokul Raghavan explains why this was the bet we wanted to make in mobile power. Chapters: 00:30 — Why S2G Invested in ANA 05:18 — From Registered Nurse to Co-Founder 07:37 — Betting on a "Sleepy" Distribution Business 11:06 — The Invisible Industry Behind Every Job Site 14:17 — Inside EBOSS: Letting the Battery Carry the Load 18:06 — Why Nobody Did This Sooner, and the LTO Bet 21:35 — $11M to $400M on a Single Outside Check 25:09 — Europe, FlexBoost, and Powering the Super Bowl This episode originally appeared on Energy Empire. Energy Empire is hosted by Jigar Shah and Jamie Nolan, and covers the people, capital, and decisions shaping the future of energy. Check out more of their episodes at https://www.energyempire.fm/ This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

August 27, 2026Episode 1944 min

Can Europe Remain the Protagonist of its Future with Bruno Le Maire

The longest-serving finance minister in modern French history thinks Europe's problem isn't talent, money, or ideas. It's that Europe can no longer make decisions. Bruno Le Maire joins S2G’s Sanjeev Krishnan and Frédéric Michel, former chief strategy and communications advisor to Emmanuel Macron, to explain how power shifted away from elected governments, toward Washington, Beijing, tech giants, and the bond market, and why Europe's institutions were built for a world that no longer exists. His fixes are structural, with a core group of six countries moving on defense, chips, and AI, competition rules that let European champions form, and a capital markets union that starts with five willing members instead of waiting for 27. He's candid about the risks at home, with French yields above 4% and debt service climbing toward €100 billion a year, and about why voters are drifting to parties that promise rupture. Yet he ends on conviction: Europe remains the best place to live, and with a handful of big decisions, it can still compete. A rare insider account that is explicit about the problems but stays constructive and hopeful. 02:07 — Power has moved from governments to tech and finance 05:17 — When Musk cut Russia off from Starlink 07:24 — Aging, warming, and AI arriving at once 10:36 — Why voters reject pension reform 13:01 — Let six countries decide instead of twenty-seven 16:41 — France has 48 ministers and needs 10 19:18 — French bond yields and what could break 24:23 — Debt, nuclear power, and German rearmament 28:27 — Three things Europe needs to build a hyperscaler 36:50 — The rise of the far right, and why he's still optimistic This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

August 13, 2026Episode 1830 min

What Biotech Can Teach Us About Long Duration Investing

Every investor in long-duration, capital-intensive sectors eventually faces the same question: what do you do when the exit markets close and your companies still need years of funding? Keith Crandell answered it the hard way. His firm, ARCH Venture Partners, started as a University of Chicago experiment with a $9 million fund that took 15 months to raise, then hit biotech's "nuclear winter," leading to six years in the 1990s with just a single portfolio IPO. In this conversation with S2G's Aaron Rudberg from this year’s Summit, Keith walks through the strategies he has honed over the last three decades: licensing narrow "slices of salami" to strategic partners without giving away the core company, treating government grants like a syndicate member, viewing the IPO as a funding event rather than an exit, and scouring the globe to consolidate the IP and talent of the dozen teams working on the same breakthrough. Decades later, that playbook produced the Metsera sale to Pfizer. Keith closes with where he thinks GLP-1s and longevity science go from here. Read the full Financing Reality Report . Chapters: 02:20 — How ARCH Got Its Start 07:20 — Raising a $9 Million Fund the Hard Way 09:10 — When an IPO Isn’t Really an Exit 10:40 — Surviving Biotech’s “Nuclear Winter” 14:30 — The Ladder of Capital 17:20 — Why Your First Investors Matter 21:00 — Learning to Fund the Long Haul 27:40 — What Comes After GLP-1s? Keith Crandell was not compensated for participating in this podcast or for speaking at the S2G Summit. S2G reimbursed Keith's reasonable travel and lodging expenses to attend the Summit, where this presentation was originally delivered. This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .

July 30, 2026Episode 1724 min

The Riches in the Niches: Financing the Long Tail of the Real Economy

At S2G, we believe the best returns over the next 30 years won't come from crowded deals, but from building the financial infrastructure for businesses that don't fit traditional funding categories. But how do you finance a business that doesn't fit into any box the capital markets recognize? Paul Lisiak has built a career and a $1.8 billion firm, doing exactly that. Recorded live at this year's S2G Summit, Sanjeev sits down with Paul, founder and managing partner of Metropolitan Partners, a private credit firm that finances niches many investors never think about, from mobile game revenues to literary rights to non-vocal music royalties. Paul shares his "fishing holes" playbook: find an underfished niche, do the hard underwriting work others won't, earn the complexity premium, and move on once the crowd shows up. Along the way, he explains why he passed on YouTube royalties and funeral homes, why he's now looking at housing affordability, trade schools, and even a bowling alley roll-up, and why he believes we've moved from a K-shaped to an "E-shaped" economy. This episode will leave you with a sharper eye for the opportunities hiding in plain sight and a better sense of what it actually takes to be the first one there. Read the full Financing Reality Report . Paul Lisiak was not compensated for participating in this podcast or for speaking at the S2G Summit. S2G reimbursed Paul's reasonable travel and lodging expenses to attend the Summit, where this presentation was originally delivered. This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. The views expressed herein are opinions based on certain assumptions and subject to change. For more important information, please see s2ginvestments.com/disclosures .