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Myosin.xyz

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Episodes

89

Latest episode

Aug 2026

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EN-US

About the show

Myosin.xyz is the ultimate decentralized marketing network, accelerating the onchain revolution to create a more equitable internet. Subscribe to listen to our shows Chain Reactions & Netcetera. Chain Reactions is a weekly livestream where we talk about the latest in blockchain, break down interesting marketing campaigns, and have fun w/ourselves, members, and friends of Myosin. Netcetera is a series where we talk to leaders at the forefront of innovation, whether at traditional brands, web3 or AI companies, to demystify the innovations sharing the new internet.

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August 14, 2026Episode 51 hr 43 min

CR Live #0005: Reddit AI data deals, GEO is a Scam, Creators = IP and more

The first live marketing talk show goes under the hood of the growth machines running frontier tech. No hype, no founder worship, just marketers who have done the work telling you what they actually see.​Every other week, a rotating crew goes live to decode the moves everyone in marketing is quietly talking about, break down a real product in real time, take hard sides on a hot take that matters, and put their own instincts under pressure with no time to hide behind a framework.​This week we open on Reddit turning on itself: its own ads boss admits he's not sure the data moat he sells advertisers is still exclusive, now that the company is licensing community data to OpenAI and Google. Then Olly takes GEO apart and makes the case that "AI visibility" is mostly repackaged SEO with a shinier name. And we get into creators becoming the IP, where a 4chan post turns into a $390M franchise and studios scramble to own culture nobody really can. Plus more.This is Chain Reactions, reborn as the show from marketers to break open all the marketing around you.

August 12, 202651 min

Chain Reactions Live #0003: Google's AI Mode Ads Nobody Covered + Agent Orchestration for Growth

Google quietly shipped four new ad formats inside AI Mode, and almost nobody covered it. We did. Plus: a $13 CPC on ChatGPT ads, and Memrise's growth agent that lives entirely in Slack.CHAPTERS 00:00 Cold open 03:06 Welcome — Victoria joins, Polina returns 04:24 What's on the show today 05:30 WATERCOOLER: Sonnet 5's price hike and Fable 5's return 07:38 Token-maxing culture and the hidden cost of the price hike 10:16 Ford rehires the people it fired — to train the AI 12:47 Why the most elementary AI framing gets the most buzz 14:27 Benchmarking models on price, speed and quality before you buy 15:12 Product Hunt's June: the top tools were integrations, not standalone AI 17:30 The core stack nobody has replaced (and why Slack survived) 22:14 The vibe-coded app problem: broken back ends, ToS exposure, $20 lessons 26:01 Cannes Lions: the agency billing model everyone admits is dead 28:02 Creator activations go niche — eyeballs over follower counts 28:45 Why Victoria skipped Cannes, and the CEO as the next creator 31:04 Celebrity clout vs. an actual event strategy 33:40 AI's image rehab in marketing, and the founders paying for their own message 36:06 SheaMoisture flipped the creator brief 39:21 Why YouTube mid-roll ad reads stopped working 40:42 Google's AI Mode ads — the story nobody covered 43:03 Four new ad types, and what a business owner is actually signing up for 44:43 A $13 CPC on ChatGPT ads 46:10 Could ChatGPT just run an affiliate network instead? 49:44 MARKDOWN: Lizzie Lawley, Head of Applied AI at Memrise 50:20 From pilot, to AI companion platform, to Wombat, to Memrise 53:39 The system map: every input feeding the growth machine 56:00 Core principles: context first, cheapest capable model, disagreement as a feature 56:36 "Months of work in hours" — what it actually saved 58:36 The loops: synthesis, experiment shaping, prototyping, build ticket, human gate 1:00:41 Live demo: "It's just Slack, baby" 1:03:10 How the agent gets fresh context every single night 1:06:04 OpenClaw V1, then real engineers rebuilt it 1:07:06 The failures: how expensive it got, real quick 1:08:32 The model pricing tier system, tier by tier 1:11:19 Where the user interviews actually live (it's Google Docs) 1:13:59 The bot that spammed banana emojis, and what it taught her 1:15:54 Claude Design as a starting point for growth people who can't design 1:17:35 Why we skipped Hot Button this week 1:18:27 ADAHOLIC: the rules 1:20:22 Round 1: Ed Sheeran, a posh restaurant, and way too many forks 1:23:33 Round 2: red key, blue key, and a luxury pitch 1:26:23 Round 3: "Yo... where's Dukey?" 1:29:03 Round 4: the Mother's Day one 1:32:26 Round 5: the car ad Arnav paused a second too late 1:35:14 Round 6: puffballs, chrome nails and woodworking 1:39:07 Round 7: "a better everyday life for the many people" 1:40:41 Victoria takes the crown on her first appearance 1:41:54 CloseTHIS WEEK'S GUESTLizzie Lawley — Head of Applied AI at Memrise, co-founder of Wombat. She built a platform handling millions of simultaneous AI interactions with cost-efficient model routing, and now runs agent orchestration for Memrise's growth team. Her system pulls from transcripts, app reviews, Zendesk tickets, past experiment synthesis, Athena and BigQuery, and runs a nightly cron job so the agents never work off stale context. Methodology follows Bob Moesta's jobs to be done. The team calls it BYOB — bring your own Bobby.Ads featured in Adaholic this week: Heinz, Kia, Budweiser, Honda, Pinterest, IKEA.

August 3, 2026Episode 31 hr 17 min

Chain Reactions Live #0002: WhatsApp's New CEO, Google's A24 investment, Cursor Acquisition

Chain Reactions is the live marketing talk show from Myosin — built by operators, for operators — breaking down the marketing happening all around you with people who actually run growth.Today, Arnav is joined by the two OGs of the show, Blake and Polina, for a 90-minute run-through of the stories the Silicon Valley echo chamber is losing its mind over, a live tool teardown, a debate, and a game that exposes how many ads you consume without realizing it.What we get into:- Kunal Shah taking the WhatsApp global CEO seat — CRED, UPI, and whether messaging apps actually become the payment layer in markets like India, China, and parts of Europe- SpaceX's IPO, the 5% float, and xAI/Grok acquiring Cursor for $60B in stock — a customer-and-talent grab more than an IDE play- Why local models became the whole conversation overnight: token economics, Anthropic's pricing shift, and what the Fable/Mythos restrictions mean for anyone building on frontier models- Google's $75M move into A24, AI in filmmaking, and the creative-tooling debate (Tron, Toy Story, and the "press a button to make AI disappear" crowd)- Markdown — Polina walks through the content automation system behind her UFC prediction tool: trusted-source scraping, virality scoring, Telegram alerts, and Fal.ai image generation with a human always in the loop- Hot Button — should performance marketing report to the CFO or the CMO? A "cordial" debate that turns into a real argument about attribution, LTV, and who owns the risk- Adaholic — guess the brand and category from the ad clip. Polina runs away with it, seven wins deep.CHAPTERS00:00 Intro — welcome back, Blake & Polina01:16 Watercooler: Kunal Shah → WhatsApp global CEO (CRED, UPI, WeChat-ification)09:32 SpaceX IPO + xAI/Grok acquires Cursor for $60B20:07 The local models moment, token economics & Anthropic pricing30:19 Google's $75M into A24 + AI in film and creative38:08 Markdown: Polina's UFC content automation teardown54:32 Hot Button: should performance marketing report to CFO or CMO?1:11:16 Adaholic: name that ad#ChainReactions #GrowthMarketing #AIMarketing #GTM #PerformanceMarketing #MarketingPodcast #Myosin #MarketingStrategy #LocalModels #VibeMarketing #CMO #SpaceX #Grok #B2BMarketing #MarketingNews #GrowthMarketing #AIMarketing

July 31, 2026Episode 41 hr 35 min

Chain Reactions Live #0004: Apple vs OpenAI, Reddit the Gen Z GOAT? Google for creators? and more

Chain Reactions is Back: TBPN isn't the only game in town.The first live marketing talk show goes under the hood of the growth machines running frontier tech. ​Every other week, a rotating crew goes live to decode the moves everyone in marketing is quietly talking about, break down a real product in real time, take hard sides on a hot take that matters, and put their own instincts under pressure with no time to hide behind a framework.This week we go under the hood of the west vs east of AI models, Apple vs Open AI, Reddit marketing and google jumping on to help creators curate their discovery, we also have Jeff Marsilio on to breakdown the brand and commercials behind the Newton Foundation, and with our audience favorite segment with a guessing game based on riddles and emojis👀​This is Chain Reactions, reborn as the show from marketers, to break open all the marketing around you.

July 27, 2026Episode 11 hr 17 min

Chain Reactions Live #0001: Anthropic's Fable, Apple and Gemini's Partnership,TikTok Shop's Future

Chain Reactions is Back: TBPN isn't the only game in town.The first live marketing talk show goes under the hood of the growth machines running frontier tech. No hype, no founder worship, just marketers who have done the work telling you what they actually see.​Every other week, a rotating crew goes live to decode the moves everyone in marketing is quietly talking about, break down a real product in real time, take hard sides on a hot take that matters, and put their own instincts under pressure with no time to hide behind a framework.​The first one pulls the curtain back on Myosin itself. Blake gets into where the company is headed and what's happening behind the scenes. Matt breaks down HiveMind and how we're building AI-enabled GTM systems from the inside.​This is Chain Reactions, reborn as the show from marketers, for anyone who wants to understand marketing better, without the BS hype.

March 16, 2026Episode 5252 min

From AI-Wary to AI-Enabled Marketers

In this episode, we sit down with Jay and Shane, Co-Leads of the AI-Enabled Marketer & Growth Guild at Myosin, to unpack what AI-enabled marketing actually looks like in practice. We get into how both of them found their way into crypto and marketing, why AI is no longer optional for modern marketers, and how tools like ChatGPT, Claude Code, n8n, OpenClaw, Higgsfield, and Suno are changing the way teams build, iterate, and ship. We also talk through the thinking behind the AI-Enabled Marketer Skoool community they recently launched, what they’re teaching inside it, and why the goal is not hype or course-bro fluff, but practical workflows that help marketers actually do better work. Along the way, we dig into AI literacy, automation, vibe coding, creative production, lead magnets, prompting, and the difference between just watching AI content versus actually building with it. If you’ve been feeling excited, overwhelmed, or slightly behind on AI, this one is for you. Timestamps 00:00 Intro and why AI-enabled marketing matters now 04:24 Jay’s background, how crypto clicked, and why marketing was the natural lane 06:27 Shane’s path from journalism and humanitarian work into Web3 08:41 What “AI-enabled marketing” actually means 12:15 Their current AI stack: ChatGPT, Claude, Claude Code, OpenClaw, Higgsfield, Suno, n8n, and more 15:40 Why the AI-Enabled Marketer community exists and who it’s built for 32:32 Live demo: AI literacy quiz, lead magnets, and practical marketing builds 40:50 How they’re teaching image and video generation for marketers 52:13 Rapid fire: underrated tactics, overrated tactics, and biggest lessons from the past year Show Notes Learn more: https://myosin.xyz/ai-enabled-marketer Skool: https://www.skool.com/the-ai-enabled-marketer/about

March 3, 202647 min

Why Robots Want Robot Money and What That Means for All of Us

In Episode 51 of *Chain Reactions*, we sit down with Lex Sokolin, co-founder of [Generative Ventures](https://www.genventures.xyz/) and one of the sharpest voices at the intersection of fintech, crypto, and AI. With 15 years at the frontier of financial services, from Wall Street to early robo-advisors to co-leading DeFi strategy at ConsenSys, Lex brings a rare combination of depth and directness to the conversation.We dig into his core thesis: that AI agents are becoming economic peers, and those peers need financial infrastructure built for them. Lex breaks down how blockchain has collapsed five massive verticals of financial services into a single rail, why that's both unbelievably destructive and productive, and where the real commercial opportunities sit across payments, capital markets, and asset management.The conversation gets candid fast. Lex doesn't hold back on the crypto industry's tendency to dress up vaporware in legitimate opportunity, the evolution from Olas to Virtuals to OpenClaw as each wave of agentic AI gets slightly more real, and why the race to market to agents may ultimately benefit the fewest actual humans. We also get into the Visa and MasterCard question, whether Web3 is finance's Amazon-vs-Kmart moment, and why Tether's business model might be more interesting than Stripe's.We close with Lex's personal philosophy on turning the page, borrowed from a background in visual arts, and why building beats worrying in an era of exponential change.---**Timestamps**00:00 – Welcome and intro to Lex Sokolin of Generative Ventures02:36 – From Wall Street to robo-advisors to ConsenSys and beyond05:50 – The machine economy thesis and where the real opportunities sit08:29 – How blockchain collapsed five financial verticals into one rail10:56 – AI-first companies vs crypto-native firms and where they overlap13:42 – Latest developments and the pace of change in agentic AI14:24 – S-curves vs exponentials and why it matters for AI capabilities16:45 – The evolution from Olas to Virtuals to Lobsters20:41 – Will Visa and MasterCard be disintermediated by agents?27:39 – Amazon vs Kmart: is Web3 finance's greenfield moment?31:40 – How do you market to agents? The dystopian and practical answer36:54 – Spotting AI content in the wild and the normie gap38:32 – What Lex has changed his mind on about decentralization43:25 – What gets Lex most excited and most concerned heading into 202647:48 – The trap of AI consumption vs production49:27 – Biggest professional learning: being unafraid to turn the page---**Show Notes & Mentions**- 🧠 [Generative Ventures](https://www.genventures.xyz/) – Early-stage fund focused on the machine economy and robot money- 🧵 [Lex Sokolin on X](https://x.com/LexSokolin)- 📰 [Fintech Blueprint](https://www.fintechblueprint.com/) – Lex's newsletter reaching 110,000+ readers

February 17, 202650 min

Building State Street for Digital Assets: How Lagoon Is Powering the On-Chain Vault Economy

In Episode 50 of Chain Reactions , Blake sits down with Nadia Sergujuk, Co-Founder of Lagoon , the permissionless vault management infrastructure that wants to become the State Street of digital assets. With a background spanning Danish law schools, PWC Legal in London, hedge funds managing $10B+ in AUM, and VC investing in deep tech, Nadia brings a rare cross-disciplinary lens to one of the fastest-growing categories in DeFi. We cover: – How Nadia went from law school in Copenhagen to hedge funds in London to co-founding an on-chain vault protocol– What vault management infrastructure actually is and why every stablecoin dollar eventually needs one– Why Lagoon's team put their own capital in first and how word of mouth drove early traction– The stablecoin explosion, neo banks in emerging markets, and why the digital dollar is eating the world– Privacy on-chain, the rise of institutional chains, and what keeps Nadia up at night (hint: quantum computing and the triple bubble) We also get into regulation as a tailwind, why Japan is the most slept-on institutional market in crypto, the innovator's dilemma facing Western Union and Visa, and why founder-led marketing beats KOLs every time. Timestamps 00:00 – Going live and Nadia joins from the Swiss Alps 04:00 – From law school in Denmark to hedge funds in London 06:30 – First exposure to Bitcoin in 2016 (and not buying it) 08:20 – COVID, DeFi summer, and going all in on crypto 09:30 – Meeting co-founder Remy at a conference in Bogota 11:27 – What is Lagoon? Vault management infrastructure explained 13:30 – Why permissionless and open source matters for trust 16:26 – Business model: 10% of vault fees plus SaaS services 18:00 – Go-to-market: putting your own money in the vaults first 20:45 – BlackRock, Fidelity, and the TradFi wave coming on-chain faster than expected 22:23 – Why regulation is actually a tailwind for Lagoon 25:36 – Japan as the most slept-on institutional crypto market 28:00 – Neo banks, stablecoin yield, and serving emerging markets 30:30 – Why the digital dollar is irresistible in LatAm, Africa, and Southeast Asia 37:00 – Conference circuit: DAF London, DAS New York, and founder-led presence 40:06 – What keeps Nadia up at night: quantum compute and the triple bubble 45:23 – Chain landscape: Solana's DeFi renaissance and BTCFi's comeback 48:04 – Privacy on-chain: why institutions need it and how Lagoon will enable it 51:35 – Rapid fire: founder-led marketing, KOLs, Merkl, and the power of people Show Notes & Mentions 🔗 Lagoon – Permissionless vault management infrastructure for digital assets 🧵 Nadia on X 🧵 Lagoon on X 🏔️ DAS (Digital Asset Summit) – Upcoming in March in New York

February 10, 2026Episode 4259 min

Octant & Giveth Are Proving Blockchain is Doing Real Good

In Episode 49 of Chain Reactions , we sit down with Mashal Waqar, Head of Marketing at Octant , and get a surprise drop-in from Griff Green, Founder of Giveth , to dig into how public goods funding actually works on Ethereum and why it matters more now than ever. We cover: – How Octant's model works: lock GLM, earn ETH, and choose to fund public goods or keep the yield– The surprisingly heated debate over what counts as a "public good" (yes, Pizza DAO came up)– Why blockchain unlocks speed, transparency, and community-driven capital allocation that traditional grants can't match– Griff's wild story of The DAO hack, how edge case funds turned into $200M+, and the launch of the new DAO Security Fund– The case for an Ethereum security coalition and why L2s need to fund shared infrastructure Mashal shares her journey from running a media company with tens of millions of readers to burning out, discovering crypto through NFTs and Gitcoin, and co-authoring the first State of Web3 Grants report. We also get into real-world impact stories, from funding water filters in Gaza to helping doctors in Syria get paid through crypto, and why sustainable funding through DeFi yield beats depleting treasuries. Plus, a great riff on AI in public goods, the Zakat use case for crypto, and why execution beats everything. Timestamps 00:00 – Intro and what's on everyone's timeline right now02:08 – Welcome to Chain Reactions and introducing Mashal from Octant03:54 – Mashal's journey from media founder to crypto marketer06:28 – How NFTs and Crypto Covens pulled her back into Web308:53 – Co-authoring the first State of Web3 Grants report and discovering Octant10:25 – What Octant is and how the GLM staking model works13:15 – What actually counts as a public good (and the Pizza DAO debate)16:49 – The $1M Ethereum creator round and lessons from vetting 1,000+ applications18:30 – DeFi vaults, sustainable funding, and the new StreamVote experiment23:30 – Why blockchain unlocks faster, more transparent funding than traditional grants26:34 – Remittances, financial access, and the personal case for crypto in emerging markets33:24 – Griff joins: founding Giveth, The DAO hack, and rescuing $200M+ in edge case funds39:21 – The multiplier effect and why matching makes it hard not to donate44:18 – Launching the DAO Security Fund inspired by Octant's model48:45 – AI experiments at Octant, building with AI, and the case for AI in public goods56:29 – Vitalik's L2 tax tweet, Ethereum sustainability, and the need for a security coalition1:00:00 – Rapid fire: execution beats everything and don't count your chickens Show Notes & Mentions 🧠 Octant – Public goods funding platform on Ethereum 🎁 Giveth – Donation platform and public goods movement since 2016 🧵 Mashal on X 🧵 Griff on X 🧵 Octant on X 🧵 Giveth on X 🏗️ DAO Security Fund – Griff's new project to secure DAO funds and fund Ethereum security 🪙 Golem / GLM – Token powering Octant's staking and funding model 🌱 Gitcoin – Grants platform for open source and public goods 🍕 Pizza DAO – Community funding pizza parties worldwide (public good or not?) 🤖 Virtuals / 60days.ai – AI agent launchpad mentioned by Griff ⭐ Stellar – Referenced for crypto-powered aid to doctors in Syria 📊 [Blockchain for Good Report]( https://docsend.com/v/9dm2p/myosin-blockchainsforgood ]( https://docsend.com/v/9dm2p/myosin-blockchainsforgood )) – Myosin's collaborative research report on blockchain impact

January 27, 2026Episode 491 hr 2 min

Chain Reactions Ep.48 Ben from Rootstock

In Episode 48 of Chain Reactions, we sit down with Ben Sanders, Chief Growth Officer at [Rootstock Labs](https://rootstock.io/), to unpack what it takes to grow the oldest Bitcoin sidechain in an industry obsessed with short-term wins.Ben came into crypto with zero degen credentials. His background spans management consulting at Bain, go-to-market at WorldPay ahead of their IPO, and executive roles at fintech startups like Chipper Cash. He joined Rootstock for an interim role and ended up staying to lead growth for a chain that's been quietly building Bitcoin programmability for nearly a decade.**We cover:**- How Ben learned Bitcoin, crypto, and Rootstock all at once (with no prior Web3 experience)- The origin of Rootstock: Argentinian Bitcoiners building EVM compatibility on Bitcoin before it was cool- Why Rootstock is the "next best thing to Bitcoin" with 90% of Bitcoin's hash rate- The 3 A's framework for growth: Awareness, Attractiveness, Accessibility- Market entry strategies for Korea (retail, CEX listings) vs Japan (institutional, relationship-driven)- Rootstock Institutional and the $260B opportunity in dormant Bitcoin- Why long-term brand building is the most underrated tactic in Web3We also get into TradFi-DeFi convergence, why airdrops are overrated, and what it means to "run your own race" when every project around you is chasing flavor-of-the-month narratives.---**Timestamps**00:00 – Intro and getting started02:00 – Ben's path: Bain, WorldPay, fintech startups, zero crypto background05:30 – Learning Bitcoin, crypto, and Rootstock all at once07:30 – The shift back to utility and self-sovereignty of money09:30 – What is Rootstock: Argentinian Bitcoiners and programmable Bitcoin11:30 – Rootstock vs Rootstock Labs vs RIF token explained14:00 – First priority as CGO: interoperability and on-ramps17:00 – Why Rootstock over other Bitcoin L2s (safety, security, hash rate)20:00 – Bitcoin holders vs retail degens: different audiences, different approaches24:00 – The 3 A's framework: Awareness, Attractiveness, Accessibility26:00 – Market entry into Korea and Japan with Myosin28:30 – Korea Blockchain Week and the Korbit listing31:00 – 2026 focus: consolidation over expansion32:30 – Rootstock Institutional and unlocking $260B in dormant Bitcoin40:00 – TradFi and DeFi convergence: the industry is finally catching up44:00 – Where Rootstock fits as the space matures47:00 – Alpha for Bitcoin holders: what's coming in the next 6-9 months51:00 – Rapid fire: most underrated marketing tactic (long-term brand building)53:30 – Rapid fire: most overrated tactic (airdrops, renting TVL)55:30 – Projects doing it right: Morpho, Midas, Wheeler57:30 – Biggest learning: stay focused, run your own race---**Show Notes & Mentions**- 🔗 [Rootstock](https://rootstock.io/) – The longest-running Bitcoin sidechain with EVM compatibility- 🧵 [Rootstock on X](https://x.com/rootaboratory)- 🪙 [RIF Token](https://rif.technology/) – Governance and utility token for the Rootstock ecosystem- 🏦 [Rootstock Institutional](https://www.rootstocklabs.com/institutional/) – Institutional Bitcoin deployment solutions- 🇰🇷 [Korbit](https://korbit.co.kr/) – Korean centralized exchange where RIF is now listed- 🌉 [LayerZero](https://layerzero.network/) – Cross-chain interoperability protocol- 💵 [USDT Zero](https://tether.to/) – Stablecoin integration for Rootstock- 🏛️ [Morpho](https://morpho.org/) – Lending protocol- 🪙 [Midas](https://midas.app/) – Real world assets protocol- 📊 [Wheeler](https://wheeler.fi/) – Lending protocol- 🥩 [Steakhouse Finance](https://steakhouse.financial/) – DeFi analytics and strategy

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