Episodes
92
Latest episode
Oct 2026
Language
EN-US
Myosin is a network of 100+ AI-enabled marketers. We build AI growth systems inside revenue and marketing teams, and share what we learn. Chain Reactions Live is our show on what’s changing in AI and growth, and what it means for your team. Each episode covers the news, our takes on it, and demos of the tools we use. YouTube: youtube.com/@myosin_xyz The Myosin Weekly newsletter: themyosinweekly.beehiiv.com Myosin Media: https://myosin.xyz/media Earlier Chain Reactions and Netcetera episodes, from our fintech and blockchain years, are still in the feed.
This week: agents that work for days, ads nobody actually saw, a brand ditching AI on purpose, and the end of short-form. Then Matt Mason, CMO of KUNGFU.AI and author of The Pirate’s Dilemma, joins us on what ethical AI looks like at scale.
This week we run a quick blitz on where marketing meets growth and revenue: AI shopping agents selling the answer as an ad slot, agents breaking per-seat pricing, and AI revenue rising while go-to-market teams shrink. Then Thibaut Hadjean, CTO of Oriane, demos live how brands can search TikTok, Instagram and YouTube by what actually shows up on screen.
This week OpenAI's Astra runs your computer while you talk to it, and Dan Held comes on to argue what money the agents actually pay in, Bitcoin or stablecoins. Cloudflare starts charging AI bots to read the web. Canva says everyone uses AI now and everyone can tell. Disney hands Marvel and Star Wars to TikTok creators. And we play Ranked or Cranked. Plus more.
A live marketing talk show that goes under the hood of the growth machines running frontier tech. No hype, no founder worship, just marketers who have done the work telling you what they actually see.Every other week, a rotating crew goes live to decode the moves everyone in marketing is quietly talking about, break down a real product in real time, take hard sides on a hot take that matters, and put their own instincts under pressure with no time to hide behind a framework.This week we open on Anthropic quietly watermarking everything Claude writes to please the EU — then admitting the mark barely works, and it's already being scrubbed off. Then agentic commerce's civil war: everyone says optimize for the AI shopping agent, while Amazon starves those same agents to drag shoppers back to its aisles. Plus a ten-foot ball of human hair rolls through NYC and the internet's first guess is "that's AI." Growth-hacking pioneer Anuj Adhiya joins us, and we play a round of Slick or Slop. Plus more.This is Chain Reactions, reborn as the show from marketers, to break open all the marketing around you.
The first live marketing talk show goes under the hood of the growth machines running frontier tech. No hype, no founder worship, just marketers who have done the work telling you what they actually see.Every other week, a rotating crew goes live to decode the moves everyone in marketing is quietly talking about, break down a real product in real time, take hard sides on a hot take that matters, and put their own instincts under pressure with no time to hide behind a framework.This week we open on Reddit turning on itself: its own ads boss admits he's not sure the data moat he sells advertisers is still exclusive, now that the company is licensing community data to OpenAI and Google. Then Olly takes GEO apart and makes the case that "AI visibility" is mostly repackaged SEO with a shinier name. And we get into creators becoming the IP, where a 4chan post turns into a $390M franchise and studios scramble to own culture nobody really can. Plus more.This is Chain Reactions, reborn as the show from marketers to break open all the marketing around you.
Google quietly shipped four new ad formats inside AI Mode, and almost nobody covered it. We did. Plus: a $13 CPC on ChatGPT ads, and Memrise's growth agent that lives entirely in Slack.CHAPTERS 00:00 Cold open 03:06 Welcome — Victoria joins, Polina returns 04:24 What's on the show today 05:30 WATERCOOLER: Sonnet 5's price hike and Fable 5's return 07:38 Token-maxing culture and the hidden cost of the price hike 10:16 Ford rehires the people it fired — to train the AI 12:47 Why the most elementary AI framing gets the most buzz 14:27 Benchmarking models on price, speed and quality before you buy 15:12 Product Hunt's June: the top tools were integrations, not standalone AI 17:30 The core stack nobody has replaced (and why Slack survived) 22:14 The vibe-coded app problem: broken back ends, ToS exposure, $20 lessons 26:01 Cannes Lions: the agency billing model everyone admits is dead 28:02 Creator activations go niche — eyeballs over follower counts 28:45 Why Victoria skipped Cannes, and the CEO as the next creator 31:04 Celebrity clout vs. an actual event strategy 33:40 AI's image rehab in marketing, and the founders paying for their own message 36:06 SheaMoisture flipped the creator brief 39:21 Why YouTube mid-roll ad reads stopped working 40:42 Google's AI Mode ads — the story nobody covered 43:03 Four new ad types, and what a business owner is actually signing up for 44:43 A $13 CPC on ChatGPT ads 46:10 Could ChatGPT just run an affiliate network instead? 49:44 MARKDOWN: Lizzie Lawley, Head of Applied AI at Memrise 50:20 From pilot, to AI companion platform, to Wombat, to Memrise 53:39 The system map: every input feeding the growth machine 56:00 Core principles: context first, cheapest capable model, disagreement as a feature 56:36 "Months of work in hours" — what it actually saved 58:36 The loops: synthesis, experiment shaping, prototyping, build ticket, human gate 1:00:41 Live demo: "It's just Slack, baby" 1:03:10 How the agent gets fresh context every single night 1:06:04 OpenClaw V1, then real engineers rebuilt it 1:07:06 The failures: how expensive it got, real quick 1:08:32 The model pricing tier system, tier by tier 1:11:19 Where the user interviews actually live (it's Google Docs) 1:13:59 The bot that spammed banana emojis, and what it taught her 1:15:54 Claude Design as a starting point for growth people who can't design 1:17:35 Why we skipped Hot Button this week 1:18:27 ADAHOLIC: the rules 1:20:22 Round 1: Ed Sheeran, a posh restaurant, and way too many forks 1:23:33 Round 2: red key, blue key, and a luxury pitch 1:26:23 Round 3: "Yo... where's Dukey?" 1:29:03 Round 4: the Mother's Day one 1:32:26 Round 5: the car ad Arnav paused a second too late 1:35:14 Round 6: puffballs, chrome nails and woodworking 1:39:07 Round 7: "a better everyday life for the many people" 1:40:41 Victoria takes the crown on her first appearance 1:41:54 CloseTHIS WEEK'S GUESTLizzie Lawley — Head of Applied AI at Memrise, co-founder of Wombat. She built a platform handling millions of simultaneous AI interactions with cost-efficient model routing, and now runs agent orchestration for Memrise's growth team. Her system pulls from transcripts, app reviews, Zendesk tickets, past experiment synthesis, Athena and BigQuery, and runs a nightly cron job so the agents never work off stale context. Methodology follows Bob Moesta's jobs to be done. The team calls it BYOB — bring your own Bobby.Ads featured in Adaholic this week: Heinz, Kia, Budweiser, Honda, Pinterest, IKEA.
Chain Reactions is the live marketing talk show from Myosin — built by operators, for operators — breaking down the marketing happening all around you with people who actually run growth.Today, Arnav is joined by the two OGs of the show, Blake and Polina, for a 90-minute run-through of the stories the Silicon Valley echo chamber is losing its mind over, a live tool teardown, a debate, and a game that exposes how many ads you consume without realizing it.What we get into:- Kunal Shah taking the WhatsApp global CEO seat — CRED, UPI, and whether messaging apps actually become the payment layer in markets like India, China, and parts of Europe- SpaceX's IPO, the 5% float, and xAI/Grok acquiring Cursor for $60B in stock — a customer-and-talent grab more than an IDE play- Why local models became the whole conversation overnight: token economics, Anthropic's pricing shift, and what the Fable/Mythos restrictions mean for anyone building on frontier models- Google's $75M move into A24, AI in filmmaking, and the creative-tooling debate (Tron, Toy Story, and the "press a button to make AI disappear" crowd)- Markdown — Polina walks through the content automation system behind her UFC prediction tool: trusted-source scraping, virality scoring, Telegram alerts, and Fal.ai image generation with a human always in the loop- Hot Button — should performance marketing report to the CFO or the CMO? A "cordial" debate that turns into a real argument about attribution, LTV, and who owns the risk- Adaholic — guess the brand and category from the ad clip. Polina runs away with it, seven wins deep.CHAPTERS00:00 Intro — welcome back, Blake & Polina01:16 Watercooler: Kunal Shah → WhatsApp global CEO (CRED, UPI, WeChat-ification)09:32 SpaceX IPO + xAI/Grok acquires Cursor for $60B20:07 The local models moment, token economics & Anthropic pricing30:19 Google's $75M into A24 + AI in film and creative38:08 Markdown: Polina's UFC content automation teardown54:32 Hot Button: should performance marketing report to CFO or CMO?1:11:16 Adaholic: name that ad#ChainReactions #GrowthMarketing #AIMarketing #GTM #PerformanceMarketing #MarketingPodcast #Myosin #MarketingStrategy #LocalModels #VibeMarketing #CMO #SpaceX #Grok #B2BMarketing #MarketingNews #GrowthMarketing #AIMarketing
Chain Reactions is Back: TBPN isn't the only game in town.The first live marketing talk show goes under the hood of the growth machines running frontier tech. Every other week, a rotating crew goes live to decode the moves everyone in marketing is quietly talking about, break down a real product in real time, take hard sides on a hot take that matters, and put their own instincts under pressure with no time to hide behind a framework.This week we go under the hood of the west vs east of AI models, Apple vs Open AI, Reddit marketing and google jumping on to help creators curate their discovery, we also have Jeff Marsilio on to breakdown the brand and commercials behind the Newton Foundation, and with our audience favorite segment with a guessing game based on riddles and emojis👀This is Chain Reactions, reborn as the show from marketers, to break open all the marketing around you.
Chain Reactions is Back: TBPN isn't the only game in town.The first live marketing talk show goes under the hood of the growth machines running frontier tech. No hype, no founder worship, just marketers who have done the work telling you what they actually see.Every other week, a rotating crew goes live to decode the moves everyone in marketing is quietly talking about, break down a real product in real time, take hard sides on a hot take that matters, and put their own instincts under pressure with no time to hide behind a framework.The first one pulls the curtain back on Myosin itself. Blake gets into where the company is headed and what's happening behind the scenes. Matt breaks down HiveMind and how we're building AI-enabled GTM systems from the inside.This is Chain Reactions, reborn as the show from marketers, for anyone who wants to understand marketing better, without the BS hype.
In this episode, we sit down with Jay and Shane, Co-Leads of the AI-Enabled Marketer & Growth Guild at Myosin, to unpack what AI-enabled marketing actually looks like in practice. We get into how both of them found their way into crypto and marketing, why AI is no longer optional for modern marketers, and how tools like ChatGPT, Claude Code, n8n, OpenClaw, Higgsfield, and Suno are changing the way teams build, iterate, and ship. We also talk through the thinking behind the AI-Enabled Marketer Skoool community they recently launched, what they’re teaching inside it, and why the goal is not hype or course-bro fluff, but practical workflows that help marketers actually do better work. Along the way, we dig into AI literacy, automation, vibe coding, creative production, lead magnets, prompting, and the difference between just watching AI content versus actually building with it. If you’ve been feeling excited, overwhelmed, or slightly behind on AI, this one is for you. Timestamps 00:00 Intro and why AI-enabled marketing matters now 04:24 Jay’s background, how crypto clicked, and why marketing was the natural lane 06:27 Shane’s path from journalism and humanitarian work into Web3 08:41 What “AI-enabled marketing” actually means 12:15 Their current AI stack: ChatGPT, Claude, Claude Code, OpenClaw, Higgsfield, Suno, n8n, and more 15:40 Why the AI-Enabled Marketer community exists and who it’s built for 32:32 Live demo: AI literacy quiz, lead magnets, and practical marketing builds 40:50 How they’re teaching image and video generation for marketers 52:13 Rapid fire: underrated tactics, overrated tactics, and biggest lessons from the past year Show Notes Learn more: https://myosin.xyz/ai-enabled-marketer Skool: https://www.skool.com/the-ai-enabled-marketer/about
Claim this listing to keep it up to date, reach guests who want to pitch you, and manage bookings with Guestify.
Claim this listing
Brian Rose
Nikki Lewallen Gregory
Jordan
Kerry Walsh
Dr. Melissa Parks
Kristin Morris
