August 17, 2026Episode 98320 min
I Ran a 50K on LSD – Sarah Rose Siskind 1/5
Sarah Siskind on running a 50K on LSD, testing drugs as performance enhancers, and why surrender matters to the psychedelic experience.
Episodes
90
Latest episode
Aug 2026
Language
EN-US
About the show
Implementing Science Fiction
Listen to episodes
August 14, 2026Episode 9524 min
Dual-Use AI, Perennial Truths & 2040 – Pedro Domingos 5/5
Dual-use AI, perennial truths in The Master Algorithm, and the satire of 2040.
August 13, 2026Episode 9425 min
Seattle, Weird Science, & The Master Algorithm – Pedro Domingos 4/5
Seattle vs Bay Area, ignored ML departments, and the quest for the Master Algorithm.
August 12, 2026Episode 9325 min
The Lab Race & the Open Research Ecosystem – Pedro Domingos 3/5
Why open research still beats closed labs in the AI talent and breakthrough race.
August 11, 2026Episode 9218 min
If It Needs a Harness Its Not AGI – Pedro Domingos 2/5
Harnesses aren’t AGI — adversarial cybersecurity, personal agents, and commoditizing the model layer.
August 10, 2026Episode 9116 min
A Better Name for Moonshot Would Be Moonshine – Pedro Domingos 1/5
Pedro Domingos on Moonshot, model distillation, and why open AI gives defenders a white-hat advantage.
August 8, 2026Episode 9016 min
The Truth About Raising Venture Capital – Jamie Wood 5/5
Jamie Wood asks Pablos what would stop him from investing in AUTONOMIC. Their conversation expands into a blunt guide to venture fundraising: fund mandates, venture-scale outcomes, timing, opaque decisions, warm introductions and why founders should not overinterpret any one investor's response. The central advice is simple and difficult—there is no enlightened fundraising algorithm, so build a large pipeline and keep taking shots on goal.
August 7, 2026Episode 8929 min
The Brain Data Flywheel – Jamie Wood 4/5
Jamie Wood asks Pablos for a direct assessment of AUTONOMIC's hardest business problems. They work through the product, behavior-change loop, proprietary data, wearable integrations, university distribution, efficacy and the operating discipline required to make those pieces reinforce one another. The result is a candid startup teardown about the difference between owning several valuable ingredients and building a flywheel that compounds.
August 6, 2026Episode 8814 min
Brain Training the next Generation – Jamie Wood 3/5
AUTONOMIC is focusing first on college and university students. Jamie Wood describes the needs of the 18-to-24-year-old market, early pilot results, institutional buyers and the practical challenge of reaching students before they hit a crisis. She and Pablos also explore how an AI coach could translate research into short, relevant guidance and why scaling the science matters just as much as proving it works.
August 5, 2026Episode 8722 min
A Personal Trainer for Your Brain – Jamie Wood 2/5
Jamie Wood explains how AUTONOMIC turns neuroscience into a short, adaptive coaching loop. The system asks a small set of behavior-linked questions, identifies a user's goal, recommends a practical intervention and measures what happens next. Jamie and Pablos discuss why long assessments fail, how personalization can improve over time, what evidence users actually trust and why a scientifically sound product still has to compete with the opinions of random humans on the internet.
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