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Latent Space: The AI Engineer Podcast

Latent Space: The AI Engineer Podcast

Hosted by Latent.Space

TechnologyBusinessInterviews guests

Episodes

237

Latest episode

Oct 2026

Language

EN

About the show

The podcast by and for AI Engineers! In 2025, over 10 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0. We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you'll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny (George Hotz), Databricks/MosaicML (Jon Frankle), Modular (Chris Lattner), Answer.ai (Jeremy Howard), et al. Full show notes always on https://latent.space Sponsorship and business inquiries: business@latent.space www.latent.space

Listen to episodes

60 recent
October 27, 20261 hr 46 min

How Anthropic ships the #1 LLM in the World safely: Separating the Brain from the Hands

<p>Katelyn Lesse and Angela Jiang join Latent Space to explain the engineering behind the Claude Platform: launching Opus 5.5, separating the model’s “brain” from the agent’s “hands,” scaling APIs, and building reliable managed agents. A new introduction ...</p>

October 26, 202616 min

⚡ An Eval for AI Scientists That Knows the Answer Key - Ian Quigley, Leash Bio

<p>Watch the full show on YouTube: https://www.youtube.com/watch?v=vhPCo-8K78U</p>

October 22, 20261 hr 25 min

Why AI Compute Comes in Rectangles — Erik Bernhardsson, Modal CEO

<p>Warm welcome to Basil Chatha, our newest cohost from the Forward Deployed side of the AI Engineering world! We’ll be ramping up a new show with him and couldn’t pass up an interview with Modal’s CEO Eric on the occasion of their monster Series D! Two y...</p>

October 22, 202626 min

The Recommendation Engine for Commodity Traders — Anekha Sokhal, Moshi

<p>Anekha Sokhal, CEO of Moshi, joins swyx to discuss building a recommendation engine for commodity traders, turning market data into useful signals, and designing AI that fits users’ workflows. Watch: YouTube · Moshi · Anekha 0:00 AI Engineer New York a...</p>

October 21, 202643 min

AI for the Fortune 2000: How Tenex Builds an AI-Native SDLC — Alex Lieberman & CJ Hess

<p>Alex Lieberman and CJ Hess join swyx at AI Engineer New York to discuss Tenex’s approach to AI-native engineering, paying for outcomes, MetaHarness, enterprise AI adoption and rebuilding SaaS. Show notes: Tenex: https://www.tenex.co/ Building an AI-nat...</p>

October 20, 202636 min

The Programmable Data Center — Evan Conrad, SF Compute

<p>This was recorded on the sidelines of the new Compute Trading track at AIE NYC. Catch us next at AIE CODE, our last flagship for the top agentic engineers in the world. In the early days of cloud, former guest Martin Casado made something so disruptive...</p>

October 14, 20261 hr 49 min

🔬 Lab-in-the-Loop at Compute Speed — Ian Quigley, Leash Bio

<p>A few years ago I stumbled upon Leash Bio’s Substack, and was hooked. Be it their Kaggle competition that showed that no, we really haven’t solved protein-ligand binding, or their crazy discovery that knowing a molecule’s author is perhaps all you need...</p>

October 13, 20261 hr 11 min

Dyna-2: General Purpose Physical Agents with Hour-Long Autonomy — Jason Ma, Dyna Robotics

<p>Watch along AIE NYC and join us at AIE CODE in SF next month! This episode includes a live demo of the Taku robot that is best enjoyed on YouTube. Last month, Dyna made waves by announcing Dyna-2, a world-action model pre-trained on one million hours o...</p>

October 10, 202631 min

🔬 Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub

<p>From the Bitter Lesson of AI scaling to the unsolved mysteries of protein folding, Google DeepMind’s Pushmeet Kohli and Biohub’s Sal Candido are rethinking what it takes to build AI that truly understands biology. In this special panel moderated by Bra...</p>

October 8, 20261 hr 23 min

🔬 Synthesis Superintelligence: from Semiconductors to Superconductors — Periodic Labs’ Liam Fedus and Ekin Dogus Cubuk

<p>It’s hard to believe that Periodic was only launched last September: One year later, it is considered one of the pre-eminent AI scientist labs, with dizzying talent density and astonishing progress in the autonomous lab buildout: Most people are famili...</p>

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