Future of Life Institute Podcast

Hosted by Future of Life Institute

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269

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Jun 2026

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About the show

The Future of Life Institute (FLI) is a nonprofit working to reduce global catastrophic and existential risk from powerful technologies. In particular, FLI focuses on risks from artificial intelligence (AI), biotechnology, nuclear weapons and climate change. The Institute's work is made up of three main strands: grantmaking for risk reduction, educational outreach, and advocacy within the United Nations, US government and European Union institutions. FLI has become one of the world's leading voices on the governance of AI having created one of the earliest and most influential sets of governance principles: the Asilomar AI Principles.

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June 12, 20261 hr 8 min

How AI Companions Trap Users Through Addictive Design (with Claire Boine)

Claire Boine is an assistant professor in technology, law, and AI governance at the European University Institute. She joins the podcast to discuss AI companions and human attachment. The conversation examines how design choices and free-to-start business models can foster dependency, expose intimate data, and blur the lines between therapy, romance, and manipulation. We also cover risks for children and teens, gaps in EU and US law, and why AI policy should distinguish technical alignment from incentives and social harms.LINKS:Claire Boine WebsiteSuccessif Organization WebsiteCHAPTERS:(00:00) Episode Preview(01:06) Introducing Claire Boan(02:05) Companion app designs(06:23) Feelings and freemium(14:28) Users, attachment, harms(25:06) Age-based risks(35:18) Future relationship norms(41:05) Legal loopholes today(44:19) Rethinking alignment framing(57:19) Narratives and fiduciaries(01:05:47) Collective policy actionPRODUCED BY:https://aipodcast.ingSOCIAL LINKS:Website: https://podcast.futureoflife.orgTwitter (FLI): https://x.com/FLI_orgTwitter (Gus): https://x.com/gusdockerLinkedIn: https://www.linkedin.com/company/future-of-life-institute/YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/Apple: https://geo.itunes.apple.com/us/podcast/id1170991978Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

May 26, 20261 hr 13 min

Why AI Chatbots Are a Rival to the Family (with Michael Toscano)

Michael Toscano is a Senior Fellow at the Institute for Family Studies and Director of its Family First Technology Initiative. He joins the podcast to discuss family-centered AI policy. The conversation covers AI companions, self-harm risks, sexualized chatbots, education, smartphones in schools, and why "infinite patience" can harm children's growth. Toscano also explains Catholic social teaching, public pushback against rapid AI deployment, and why society-wide governance may be needed to keep technology accountable to families. LINKS:Michael ToscanoCHAPTERS: (00:00) Episode Preview (01:12) Family centered AI (09:54) Companion design harms (17:23) Technology and family (25:48) Society wide governance (33:09) Catholic AI response (39:44) Double movement politics (49:36) Technology mythos challenged (59:48) Competition and control PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://podcast.futureoflife.org Twitter (FLI): https://x.com/FLI_org Twitter (Gus): https://x.com/gusdocker LinkedIn: https://www.linkedin.com/company/future-of-life-institute/ YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/ Apple: https://geo.itunes.apple.com/us/podcast/id1170991978 Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

May 11, 20261 hr 36 min

Why We Should Build AI Tools, Not AI Replacements (with Anthony Aguirre)

Anthony Aguirre is the CEO of the Future of Life Institute. He joins the podcast to discuss A Better Path for AI, his essay series on steering AI away from races to replace people. The conversation covers races for attention, attachment, automation, and superintelligence, and how these can concentrate power and undermine human agency. Anthony argues for purpose-built AI tools under meaningful human control, with liability, access limits, external guardrails, and international cooperation.LINKS:A Better Path for AIWhat You Can DoCHAPTERS: (00:00) Episode Preview (01:03) Attention, attachment, automation (13:58) Superintelligence power race (26:39) Escaping replacement dynamics (40:15) Pro-human tool AI (53:30) Guardrails and verification (01:03:24) Defining pro-human AI (01:10:37) Agents and accountability (01:17:28) International AI cooperation (01:25:28) Rethinking AI alignment (01:32:43) Optimism and action PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://podcast.futureoflife.org Twitter (FLI): https://x.com/FLI_org Twitter (Gus): https://x.com/gusdocker LinkedIn: https://www.linkedin.com/company/future-of-life-institute/ YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/ Apple: https://geo.itunes.apple.com/us/podcast/id1170991978 Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

May 7, 20261 hr 7 min

How to Govern AI When You Can't Predict the Future (with Charlie Bullock)

Charlie Bullock is a Senior Research Fellow at the Institute for Law and AI. He joins the podcast to discuss radical optionality: how governments can prepare for very advanced AI without locking in premature rules. The conversation covers why law often trails technology, and how transparency, reporting, evaluations, cybersecurity standards, and expanded technical hiring could help. We also discuss private oversight, state versus federal rules, and the risk of concentrating power in companies or government.LINKS:Radical Optionality websiteCharlie BullockCHAPTERS: (00:00) Episode Preview (01:04) The pacing problem (06:18) Defining radical optionality (11:03) Assumptions under uncertainty (16:00) Industry convenience concerns (20:41) Political will realities (26:48) Private governance limits (30:28) Government misuse risks (36:29) Balancing institutional power (42:25) Transparency and reporting (49:35) Evaluations, security, talent (58:26) State law preemption (01:04:20) Historical nuclear analogies PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://podcast.futureoflife.org Twitter (FLI): https://x.com/FLI_org Twitter (Gus): https://x.com/gusdocker LinkedIn: https://www.linkedin.com/company/future-of-life-institute/ YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/ Apple: https://geo.itunes.apple.com/us/podcast/id1170991978 Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

April 29, 20261 hr 24 min

Why AI Is Not a Normal Technology (with Peter Wildeford)

Peter Wildeford is Head of Policy at the AI Policy Network, and a top AI forecaster. He joins the podcast to discuss how to forecast AI progress and what current trends imply for the economy and national security. Peter argues AI is neither a bubble nor a normal technology, and we examine benchmark trends, adoption lags, unemployment and productivity effects, and the rise of cyber capabilities. We also cover robotics, export controls, prediction markets, and when AI may surpass human forecasters.LINKS:Peter Wildeford BlogCHAPTERS: (00:00) Episode Preview (01:12) AI bubble debate (06:25) Normal technology question (15:31) Mythos security implications (30:47) Robotics and labor (40:27) Social economic response (48:57) Forecasting methodology (59:49) AGI policy timelines (01:11:13) Forecasting with AI PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://podcast.futureoflife.org Twitter (FLI): https://x.com/FLI_org Twitter (Gus): https://x.com/gusdocker LinkedIn: https://www.linkedin.com/company/future-of-life-institute/ YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/ Apple: https://geo.itunes.apple.com/us/podcast/id1170991978 Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

April 17, 202654 min

Why AI Evaluation Science Can't Keep Up (with Carina Prunkl)

Carina Prunkl is a researcher at Inria. She joins the podcast to discuss how to assess the capabilities and risks of general-purpose AI. We examine why systems can solve hard coding and math problems yet still fail at simple tasks, why pre-deployment tests often miss real-world behavior, and how faster capability gains can increase misuse risks. The conversation also covers de-skilling, red teaming, layered safeguards, and warning signs that AIs might undermine oversight.LINKS:Carina Prunkl personal websiteCHAPTERS: (00:00) Episode Preview (01:04) Introducing the report (02:10) Jagged frontier capabilities (05:29) Formal reasoning progress (12:36) Risks and evaluation science (19:00) Funding evaluation capacity (24:03) Autonomy and de-skilling (31:32) Authenticity and AI companions (41:00) Defense in depth methods (48:34) Loss of control risks (53:16) Where to read report PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://podcast.futureoflife.org Twitter (FLI): https://x.com/FLI_org Twitter (Gus): https://x.com/gusdocker LinkedIn: https://www.linkedin.com/company/future-of-life-institute/ YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/ Apple: https://geo.itunes.apple.com/us/podcast/id1170991978 Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

April 2, 202655 min

Defense in Depth: Layered Strategies Against AI Risk (with Li-Lian Ang)

Li-Lian Ang is a team member at Blue Dot Impact. She joins the podcast to discuss how society can build a workforce to protect humanity from AI risks. The conversation covers engineered pandemics, AI-enabled cyber attacks, job loss and disempowerment, and power concentration in firms or AI systems. We also examine Blue Dot's defense-in-depth framework and how individuals can navigate rapid, uncertain AI progress.LINKS:Li-Lian Ang personal siteBlue Dot Impact organization siteCHAPTERS:(00:00) Episode Preview(00:48) Blue dot beginnings(03:04) Evolving AI risk concerns(06:20) AI agents in cyber(15:52) Gradual disempowerment and jobs(23:26) Aligning AI with humans(29:08) Power concentration and misuse(34:52) Influencing frontier AI labs(43:05) Uncertain timelines and strategy(50:18) Writing, AI, and actionPRODUCED BY:https://aipodcast.ingSOCIAL LINKS:Website: https://podcast.futureoflife.orgTwitter (FLI): https://x.com/FLI_orgTwitter (Gus): https://x.com/gusdockerLinkedIn: https://www.linkedin.com/company/future-of-life-institute/YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/Apple: https://geo.itunes.apple.com/us/podcast/id1170991978Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

March 20, 20261 hr 12 min

What AI Companies Get Wrong About Curing Cancer (with Emilia Javorsky)

Emilia Javorsky is a physician-scientist and Director of the Futures Program at the Future of Life Institute. She joins the podcast to discuss her newly published essay on AI and cancer. She challenges tech claims that superintelligence will cure cancer, explaining why biology’s complexity, poor data, and misaligned incentives are bigger bottlenecks than raw intelligence. The conversation covers realistic roles for AI in drug discovery, clinical trials, and cutting unnecessary medical bureaucracy. You can read the full essay at: curecancer.aiCHAPTERS:(00:00) Episode Preview(01:10) Introduction and essay motivation(06:30) Intelligence vs data bottlenecks(19:03) Cancer's complexity and heterogeneity(29:05) Measurement, health, and homeostasis(41:41) AI in drug development(50:13) Regulation, FDA, and innovation(01:02:58) Practical paths toward curesPRODUCED BY:https://aipodcast.ingSOCIAL LINKS:Website: https://podcast.futureoflife.orgTwitter (FLI): https://x.com/FLI_orgTwitter (Gus): https://x.com/gusdockerLinkedIn: https://www.linkedin.com/company/future-of-life-institute/YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/Apple: https://geo.itunes.apple.com/us/podcast/id1170991978Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

March 16, 20262 hr 43 min

AI vs Cancer - How AI Can, and Can't, Cure Cancer (by Emilia Javorsky)

Tech executives have promised that AI will cure cancer. The reality is more complicated — and more hopeful. This essay examines where AI genuinely accelerates cancer research, where the promises fall short, and what researchers, policymakers, and funders need to do next.You can read the full essay at: curecancer.aiCHAPTERS:(00:00) Essay Preview(00:54) How AI Can, and Can't, Cure Cancer(17:05) Reckoning with Past Failures(35:23) Misguiding Myths and Errors(59:15) AI Solutions Derive from First Principles or Data(01:31:31) Systemic Bottlenecks & Misalignments(02:08:46) Conclusion(02:14:35) The Roadmap ForwardPRODUCED BY:https://aipodcast.ingSOCIAL LINKS:Website: https://podcast.futureoflife.orgTwitter (FLI): https://x.com/FLI_orgTwitter (Gus): https://x.com/gusdockerLinkedIn: https://www.linkedin.com/company/future-of-life-institute/YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/Apple: https://geo.itunes.apple.com/us/podcast/id1170991978Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP

March 5, 20261 hr 44 min

How AI Hacks Your Brain's Attachment System (with Zak Stein)

Zak Stein is a researcher focused on child development, education, and existential risk. He joins the podcast to discuss the psychological harms of anthropomorphic AI. We examine attention and attachment hacking, AI companions for kids, loneliness, and cognitive atrophy. Our conversation also covers how we can preserve human relationships, redesign education, and build cognitive security tools that keep AI from undermining our humanity.LINKS:AI Psychological Harms Research CoalitionZak Stein official websiteCHAPTERS: (00:00) Episode Preview (00:56) Education to existential risk (03:03) Lessons from social media (08:41) Attachment systems and AI (18:42) AI companions and attachment (27:23) Anthropomorphism and user disempowerment (36:06) Cognitive atrophy and tools (45:54) Children, toys, and attachment (57:38) AI psychosis and selfhood (01:10:31) Cognitive security and parenting (01:26:15) Education, collapse, and speciation (01:36:40) Preserving humanity and values PRODUCED BY: https://aipodcast.ing SOCIAL LINKS: Website: https://podcast.futureoflife.org Twitter (FLI): https://x.com/FLI_org Twitter (Gus): https://x.com/gusdocker LinkedIn: https://www.linkedin.com/company/future-of-life-institute/ YouTube: https://www.youtube.com/channel/UC-rCCy3FQ-GItDimSR9lhzw/ Apple: https://geo.itunes.apple.com/us/podcast/id1170991978 Spotify: https://open.spotify.com/show/2Op1WO3gwVwCrYHg4eoGyP