DX Today | No-Hype Podcast & News About AI & DX

Hosted by Rick Spair

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578

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Jun 2026

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The DX Today Podcast: Real Insights About AI and Digital Transformation Tired of AI hype and transformation snake oil? This isn't another sales pitch disguised as expertise. Join a 30+ year tech veteran and Chief AI Officer who's built $1.2 billion in real solutions—and has the battle scars to prove it. No vendor agenda. No sponsored content. Just unfiltered insights about what actually works in AI and digital transformation, what spectacularly fails, and why most "expert" advice misses the mark. If you're looking for honest perspectives from someone who's been in the trenches since before "digital transformation" was a buzzword, you've found your show. Real problems, real solutions, real talk. For executives, practitioners, and anyone who wants the truth about technology without the sales pitch.

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June 16, 202611 min

The First AI Formulated Drug Reaches the Clinic: Inside Quotient Sciences' Phase I Milestone and Pharma's 2026 Inflection - June 16, 2026

Send us Fan MailThe First AI Formulated Drug Reaches the Clinic: Inside Quotient Sciences' Phase I Milestone and Pharma's 2026 Inflection Quotient Sciences, working with Intrepid Labs' machine learning, has begun what is reported as the first human clinical study of an AI designed drug formulation, after MHRA approval in the UK. Chris and Laura unpack the crucial difference between an AI designed molecule and an AI designed formulation, and what it means that there are now 200+ AI originated drug programs in clinical development. They dig into the eye catching 90 percent Phase I success claim, compressed 12 to 18 month timelines, the $2.6 billion cost problem, Insilico Medicine's idiopathic pulmonary fibrosis candidate, and the roughly 60 percent odds of a first AI originated drug approval landing in 2026 or 2027. Hosted by Chris and Laura. The DX Today Podcast brings you daily deep dives into the most consequential stories in the AI ecosystem. Send us fan mail: https://dxtoday.com/contact #AI #DrugDiscovery #HealthcareAI #ClinicalTrials #BioTech

June 16, 202611 min

DX Today AI Daily Brief - Tuesday, June 16, 2026

Send us Fan MailDX Today AI Daily Brief - Tuesday, June 16, 2026Today's briefing: Anthropic's most powerful models, Fable 5 and Mythos 5, remain offline worldwide after a US export control order, even as the company fights the Pentagon in court. SpaceX enters its second week on the Nasdaq, propelled by forced index buying ahead of likely Nasdaq 100 entry. China's open weight surge accelerates as Moonshot AI ships the trillion parameter Kimi K2.7 Code, MiniMax tops the open weight leaderboard with M3, and Z AI releases GLM five point two. Google's Gemini 3.5 Pro remains the most anticipated model still unshipped. Nvidia's Jensen Huang likens the coming AI IPOs to early Amazon, while Goldman Sachs pegs AI capital spending through twenty thirty-one at seven point six trillion dollars. OpenAI files confidentially for its IPO alongside Anthropic, the Vatican publishes an encyclical urging that AI be disarmed, Microsoft brings multi model choice and agentic Copilot Cowork to Microsoft 365, and the White House moves to federalize AI policy with a deregulatory executive order.DX Today - Your daily AI news briefing, delivered every morning.Send us fan mail#AINews #ArtificialIntelligence #OpenSourceAI #AIPolicy #DXToday

June 15, 202611 min

DX Today AI Daily Brief - Monday, June 15, 2026

Send us Fan MailDX Today AI Daily Brief - Monday, June 15, 2026Anthropic takes its most advanced Fable 5 and Mythos 5 models offline worldwide after a US export-control order, while Moonshot AI counters with an open-weights release of Kimi K2.7 Code. Mistral closes in on a roughly 20 billion euro valuation, Jeff Bezos returns to the founder's seat with a 12 billion dollar AI engineering startup called Prometheus, and Google sues a China-based cybercrime group for abusing Gemini. Visa wires its payment network into ChatGPT for agentic commerce, India's Avataar launches its Varya video model, Teradyne Robotics shows production-ready physical AI at Automate 2026, and Reco rolls out tooling to govern AI agent risk. Plus xAI's new Grok Build coding agent, Tesla bringing Grok to more countries, and Microsoft moving agentic Copilot to general availability across Word, Excel, and PowerPoint.DX Today - Your daily AI news briefing, delivered every morning.Send us fan mail#AINews #ArtificialIntelligence #Anthropic #Mistral #DXToday

June 15, 202610 min

The Seven Hundred Billion Dollar Question: Big Tech's 2026 AI Capex Sprint and the ROI Reckoning - June 15, 2026

Send us Fan MailThe Seven Hundred Billion Dollar Question: Big Tech's 2026 AI Capex Sprint and the ROI Reckoning Meta, Microsoft, Amazon, and Alphabet are on track to spend more than seven hundred billion dollars on AI infrastructure this year alone, with combined capital expenditure up roughly seventy seven percent year over year and projections topping one trillion dollars next year. Chris and Laura dig into who is spending what, why investors flinched at Amazon's two hundred billion dollar plan, and whether the monetization evidence justifies the largest corporate infrastructure buildout in modern history. Hosted by Chris and Laura. The DX Today Podcast brings you daily deep dives into the most consequential stories in the AI ecosystem. Send us fan mail: https://dxtoday.com/contact #AI #AICapex #DataCenters #BigTech #TechNews

June 14, 202612 min

TurboQuant: Google's 6x KV Cache Compression and the Quiet Economics of Long Context AI - June 14, 2026

Send us Fan MailTurboQuant: Google's 6x KV Cache Compression and the Quiet Economics of Long Context AI Google Research's TurboQuant compresses the LLM key value cache to roughly three bits per coordinate with near zero accuracy loss, delivering at least six times less memory and up to eight times faster attention on NVIDIA H100 GPUs. We unpack how its two stage design pairs a training free random rotation with a one bit correction step, why a 70B model's 128K context cache shrinks from about 40GB to under 7GB, and what that means for the cost of long context AI everywhere. Hosted by Rick Spair and Laura. The DX Today Podcast brings you daily deep dives into the most consequential stories in the AI ecosystem. Send us fan mail: https://dxtoday.com/contact #AI #LLMInference #KVCache #Quantization #TechNews

June 14, 20268 min

DX Today AI Daily Brief - Sunday, June 14, 2026

Send us Fan MailYour daily brief on the world of AI, from the DX Today media family.Today's edition: Anthropic suspends a model over safety concerns, OpenAI faces a fresh subpoena, SpaceX explores orbital data centers, Apple overhauls Siri with new AI, Amazon expands its AI push, the Pentagon deepens ties with Anthropic, Naver teams with NVIDIA, NinjaOne advances AI IT automation, Google brings Gemini to Business Profiles, Cycclone emerges, a Huawei-alumni startup launches, and Bezos-backed Prometheus makes moves.Twelve stories, twelve companies, all verified within the last twenty-four hours.Send us fan mail!#AINews #Anthropic #OpenAI #SpaceX #AppleSiri

June 13, 20269 min

DX Today AI Daily Brief - Saturday, June 13, 2026

Send us Fan MailYour daily brief on the world of A.I., from the DX Today media family.Today's edition: French A.I. lab Mistral is in talks to raise three billion euros at a twenty billion euro valuation, Jeff Bezos-backed Prometheus pulls in a staggering twelve billion dollars, KKR and NVIDIA launch the ten billion dollar Helix infrastructure fund, Google sues the makers of A.I.-powered phishing software, Florida subpoenas OpenAI over ChatGPT safety, Equal AI raises thirty million dollars, Avataar launches its Varya video model in India, Reco moves to govern Claude Enterprise agents, Bluwhale debuts an A.I.-native financial OS, Teradyne shows off physical A.I. at Automate 2026, top A.I. leaders head to the G7 summit, and U.S. states advance A.I. safeguards for minors.Twelve stories, twelve companies, all verified within the last twenty-four hours.Send us fan mail!#AINews #Mistral #OpenAI #AIFunding #AIRegulation

June 13, 202611 min

US Orders Anthropic to Pull Fable 5 and Mythos 5: Inside the Export Control Directive Over a Jailbreak Claim - June 13, 2026

Send us Fan MailUS Orders Anthropic to Pull Fable 5 and Mythos 5: Inside the Export Control Directive Over a Jailbreak Claim - June 13, 2026 On June 12, 2026, the US government issued an export control directive citing national security authorities, ordering Anthropic to suspend access to Fable 5 and Mythos 5 for any foreign national, which in practice forced a worldwide shutoff of both flagship models for all customers. Chris and Laura break down what the directive actually says, the narrow jailbreak claim behind it, Anthropic's defense in depth safety posture and 30 day data retention policy, and the company's warning that this precedent could halt frontier model deployments across the entire industry. Hosted by Chris and Laura. The DX Today Podcast brings you daily deep dives into the most consequential stories in the AI ecosystem. Send us fan mail: https://dxtoday.com/contact #AI #Anthropic #AIRegulation #ExportControls #AISafety

June 13, 202612 min

DiffusionGemma: Inside Google's Open Weight Diffusion Model That Generates Text 4x Faster - June 13, 2026

Send us Fan MailDiffusionGemma: Inside Google's Open Weight Diffusion Model That Generates Text 4x Faster - June 13, 2026 Google DeepMind just released DiffusionGemma, its first open weight diffusion language model, which refines whole blocks of text in parallel instead of predicting one token at a time. Chris and Laura dig into how discrete text diffusion works, why this 26B mixture of experts model runs on a single consumer GPU, the up to 4x speed gain, and the quality tradeoffs Google is openly acknowledging. Hosted by Chris and Laura. The DX Today Podcast brings you daily deep dives into the most consequential stories in the AI ecosystem. Send us fan mail: https://dxtoday.com/contact #AI #Google #DiffusionGemma #OpenWeights #MachineLearning

June 12, 202613 min

The AI IPO Supercycle: SpaceX's Record Debut and the Race Between OpenAI and Anthropic to Go Public - June 12, 2026

Send us Fan MailThe AI IPO Supercycle: SpaceX's Record Debut and the Race Between OpenAI and Anthropic to Go Public - June 12, 2026 SpaceX begins trading on the Nasdaq today in the largest IPO in history, a seventy five billion dollar raise at a one point seven five trillion dollar valuation with AI unit xAI at the heart of the story. Chris and Laura unpack how Anthropic's June 1 confidential S1 filing at a 965 billion dollar valuation and OpenAI's answering filing one week later have turned 2026 into an AI IPO supercycle worth roughly 3.6 trillion dollars. They explore the price war, the Oracle distribution deal, the margin and governance questions, and what it all means for everyday investors. Hosted by Chris and Laura. The DX Today Podcast brings you daily deep dives into the most consequential stories in the AI ecosystem. Send us fan mail: https://dxtoday.com/contact #AI #SpaceX #OpenAI #Anthropic #IPO