Careers in Discovery

Hosted by Tom Froggatt

BusinessInterviews guests

Website RSS feed

Episodes

100

Latest episode

Jun 2026

Language

EN-GB

About the show

Careers in Discovery is your window into the world of Pharma & Biotech. Featuring interviews each week with leaders in Drug Discovery and R&D, you’ll learn about the careers of these influential figures, the work they are doing, how they got to where they are and what advice they’d give their younger selves. Brought to you by Singular: Building Brilliant Biotechs. Connect with us at: LinkedIn: https://www.linkedin.com/company/singular-biotech/ www.singular-biotech.com

Listen to episodes

60 recent

June 10, 2026Episode 21339 min

Andrea Braun-Scherhag, SVP Global Head of Regulatory Affairs & Safety

In this episode, Andrea Braun-Scherhag, SVP and Global Head of Regulatory Affairs & Safety at Autolus, breaks down what it really takes to bring breakthrough therapies to market, especially when there’s no established playbook. From securing rapid global approvals to navigating entirely new pathways in cell and gene therapy, she shares why regulatory sits at the centre of Biotech success. Andrea challenges the common perception of regulatory as operational, revealing it instead as one of the most impactful, forward-looking functions in any biotech. She also highlights the importance of engaging regulators early, aligning teams behind a clear strategy, and putting patients at the heart of development, particularly in rare diseases.

May 27, 2026Episode 21241 min

Dan Tardiff, CAMP4 Therapeutics

What does it really take to progress from bench science to leading a Biotech platform as Chief Scientific Officer? In this episode of Careers in Discovery, Daniel Tardiff, CSO at Camp4 Therapeutics, shares a candid look at building and scaling science inside an early‑stage biotech. From his foundations in RNA biology to advancing antisense programmes for haploinsufficiency-driven neurodevelopmental disorders, Dan unpacks how translational judgement is developed over time, not taught. Key takeaway: Career progression isn’t about having perfect answers. It’s about making credible decisions under uncertainty and bringing others with you as the science scales.

May 13, 2026Episode 21140 min

Adrian Gabriel Torres, Aptadel Therapeutics

In this episode of Careers in Discovery, Adrian Gabriel Torres, Chief Scientific Officer at Aptadel Therapeutics, talks about developing RNA aptamer–based cancer therapies and leading scientific strategy in a preclinical biotech start-up. Adrian also shares his journey from academic research into industry, reflecting on the differences between academia and biotech, learning new skill sets, managing teams, and making career decisions along the way.

April 29, 2026Episode 21038 min

Rachel Abbott, Pan Cancer T

This week on Careers on Discovery, we’re joined by Rachel Abbott, CEO of Pan Cancer T. Rachel shares her journey from academic science into biotech leadership, reflecting on the pivotal moments that shaped her career - from early setbacks at university to working on T‑cell therapies that reached patients, and ultimately stepping into a first‑time CEO role. We discuss Pan Cancer T’s work developing next‑generation T‑cell therapies for solid tumours, and the challenges of translating complex science into the clinic. She also reflects on confidence, resilience, and why saying yes to opportunities before you feel ready has been a defining theme throughout her career.

April 15, 2026Episode 20939 min

Ignacio Moraga, TECregen AG

This week on Careers in Discovery, we’re joined by Ignacio Moraga, CSO and co‑founder of TECRegen. Ignacio shares his journey from Madrid to the Pasteur Institute, Stanford and Dundee, and now into biotech entrepreneurship. We talk about his work regenerating the thymus to rejuvenate the immune system, the science that inspired TECRegen, and the emerging opportunities in healthy ageing and immunotherapy. He also reflects on navigating academia, the importance of resilience, why understanding “how the game is played” matters for early scientists, and what ultimately drew him from a successful academic career into building companies.

April 1, 2026Episode 20836 min

Sarah Almond, NRG Therapeutics

This week on Careers in Discovery, we’re joined by Sarah Almond, VP of Translational Biology at NRG Therapeutics. Sarah shares her journey from early lab work to leading translational science on a first in class neurodegeneration programme. We talk about the serendipity that shaped her career, the importance of early hands-on experience, and how redundancies opened unexpected doors. Sarah reflects on leadership; from learning to give difficult feedback, to the responsibility that comes with shaping people’s day to day wellbeing, to the power of listening when managing teams. She also discusses adapting to biotech’s fast pace, navigating uncertainty, and the mindset needed to thrive in a small, mission driven environment.

March 18, 2026Episode 20753 min

Jonathan Levenson, FireCyte Therapeutics

This week on Careers in Discovery, we’re joined by Jonathan Levenson, CSO at FireCyte Therapeutics. Jonathan shares his unconventional journey from early curiosity about biology to a career spanning neuroscience research, Biotech innovation, and scientific leadership. We explore his transition from academia to industry, the lessons he learned building discovery platforms and leading translational programs, and how embracing storytelling and stakeholder alignment shaped his leadership approach. Jonathan also takes us inside the creation of FireCyte - from reimagining the retina as a window into neurodegeneration to navigating an early scientific pivot that reshaped the company’s direction. His experience is a compelling reminder that breakthrough progress often starts with challenging assumptions and following the data.

March 4, 2026Episode 20622 min

Eline Koers, AAB Therapeutics

From academic deep‑tech to the front lines of Biotech entrepreneurship - Eline Koers’ journey is a masterclass in courage, clarity, and reinvention. After years immersed in structural biology and membrane protein folding, Eline realised she wanted her work to have real‑world impact. That shift pulled her out of academia, into translational science, and eventually into founding AAB Therapeutics - a company engineering extracellular vesicles to solve one of oncology’s biggest challenges: getting drugs where they need to go. In this conversation, Eline shares the turning points that shaped her path, discussing the importance of curiosity, timing, and daring to step into the unknown - even when the success rate is small and the learning curve is steep. A brilliant episode for anyone considering a move from academia into Biotech, or thinking about building something of their own.

February 18, 2026Episode 20537 min

Marc Damelin, Alphina Therapeutics

In this episode of Careers in Discovery, Tyler is joined by Marc Damelin, Chief Scientific Officer at Alphina Therapeutics. Marc shares his journey from physics undergraduate to Biotech leader, and how a love of problem‑solving gradually drew him from yeast genetics into human disease and ultimately into drug development. After a decade in big pharma working on antibody–drug conjugates, he steps into Biotech leadership, first at Mersana and now at Alphina, where he’s pioneering a new class of ADCs built around NAMPT inhibition. Along the way, Marc reflects on choosing industry without having a clear plan, understanding what makes a role the right fit, and why being truly data‑driven is one of the most important habits a scientist can develop. An open, forward‑looking conversation about evidence, judgment and the momentum that comes from backing the right ideas at the right time.

February 4, 2026Episode 20448 min

Roxana Dreghici, Edgewise Therapeutics

From Romania to Roche to cutting-edge Biotech, Roxana Dreghici has carved out a remarkable career in drug development - and she’s done it with grit, clarity and the courage to leap into the unknown. Now VP of Musculoskeletal at Edgewise Therapeutics, Roxana shares the pivotal moments that shaped her journey: from her early days coordinating clinical trials in Texas, to building a name for herself in global pharma, and ultimately returning to her passion for muscular dystrophies. In this episode of Careers in Discovery, we talk ambition, adaptability, and the importance of knowing what you want - even before you know how to get it.