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The Real Python Podcast

The Real Python Podcast

Hosted by Real Python

TechnologyInterviews guests

Episodes

309

Latest episode

Aug 2026

Language

EN-US

About the show

A weekly Python podcast hosted by Christopher Bailey with interviews, coding tips, and conversation with guests from the Python community. The show covers a wide range of topics including Python programming best practices, career tips, and related software development topics. Join us every Friday morning to hear what's new in the world of Python programming and become a more effective Pythonista.

Listen to episodes

60 recent
August 21, 20261 hr 9 min

Navigating Silent Failures in AI: Strategies for Effective Oversight

Why do AI systems silently fail? How can you set up a system that produces results while also reviewing and validating the work? This week on the show, Calvin Hendryx-Parker returns to discuss his recent talk "Orchestrate Agentic AI: Context, Checklists, and No-Miss Reviews."

August 14, 202646 min

Improving NumPy Performance on Free-Threaded Python

What bottlenecks were preventing NumPy from scaling on free-threaded Python? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

August 7, 20261 hr 5 min

Programmatically Developing LLM Prompts With DSPy

How can you move from manually writing prompts for an LLM application toward defining them programmatically? This week on the show, Brett Kennedy returns to discuss his new book "Building LLM Applications with DSPy."

July 31, 202657 min

Should You Understand Your Entire Python Codebase?

Should you understand the entirety of your codebase? How familiar are you with Python's built-in functions? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

July 24, 202658 min

Configuring a Versatile LLM Harness & Scraping the Web With Scrapy

Which is more important, the model or the "harness" around an LLM? What are ways to assemble an efficient agentic developer workflow? This week on the show, Ayan Pahwa joins us to discuss harnessing, web scraping, and self-hosting Python applications.

July 17, 202650 min

Free-Threaded Python's History & uv in Production

How many attempts have been made to remove Python's Global Interpreter Lock (GIL)? How do they compare to the current approach? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

July 10, 202658 min

Constructing and Judging Modern Agentic Workflows

How can you improve your LLM agent systems through specification enrichment? What are the advantages of having an LLM act as a judge within an agent system? This week on the show, Senior IEEE Member and Quality Engineer Suneet Malhotra joins us to discuss building and evaluating agentic architecture.

July 3, 202645 min

Running Python Locally in a Sandbox

How do you avoid the risk of running a Python application locally that could be malicious, break your code, or leak private data? How can you create a sandboxed local environment using WASM and MicroPython? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

June 26, 202646 min

Maintaining Your Python Developer Instincts While Using LLM Tools

Do you feel like your Python skills are atrophying after using LLM coding tools? How do you add the right kind of friction into your coding routine to keep your developer instincts sharp? Christopher Trudeau is back on the show this week with another batch of PyCoder's Weekly articles and projects.

June 12, 202640 min

EuroPython 2026: Celebrating 25 Years

What's happening at EuroPython 2026? The conference celebrates its 25th anniversary this year in Kraków, Poland. This week on the show, organizers Mia Bajić and Daria Linhart Grudzien join me to discuss this year's conference.

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