Each week the Coinbase Institutional team brings you the latest news and insights to help you navigate the crypto markets.
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June 9, 202630 min
AI's Crypto Threat, Labor vs Inflation, Bitcoin Tests $60K, and Hyperliquid's Competition
Description:
We discuss why this week's macro setup favors caution, as last week's strong jobs report makes the upcoming CPI print critical to the Fed's reaction function. We cover why Bitcoin's institutional bid is being tested, with ETF outflows acting as a double-edged sword and $60K standing out as a key level to hold. We also discuss how AI-assisted discovery of a critical Zcash vulnerability is reshaping how investors price protocol security risk, and what US-regulated perps and options means for Hyperliquid.
Main sections:
(01:20 - 08:01) Labor, inflation, and the CPI setup
(08:01 - 14:02) Bitcoin's institutional bid
(14:02 - 19:35) Zcash, AI, and protocol security risk
(19:35 - 29:12) Hyperliquid's competition amidst the arrival of US perps & optionsSpeakers:
Colin Basco - Quantitative Strategist, Coinbase (X: https://x.com/colin_basco)
Greg Sutton - Head of Prime Trading, Coinbase Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
June 2, 202628 min
Crypto Options & Perps Enter America, Bitcoin Breaks Down, and Higher-for-Longer Inflation
We discuss why oil remains the key macro pressure point for crypto as Iran-conflict escalation keeps inflation risk, the dollar, and higher-for-longer Fed expectations in focus. We cover why bitcoin’s setup has weakened below $70K, with ETF outflows, weak trend signals, softer holder profitability, and exchange inflows all pointing to a more fragile market. We also discuss Coinbase bringing regulated access to crypto options and perpetual futures to the US, why that could be a major institutional market structure unlock, and why AI continues to support equities even as crypto lags.
Main sections:
(01:20 - 08:51) Oil, Iran, and stagflation risk
(08:51 - 14:21) Bitcoin’s weaker setup
(14:21 - 22:18) Crypto options and perps come to the US!
(22:18 - 27:37) AI and equity leadership
Colin Basco - Quantitative Strategist, Coinbase (X: https://x.com/colin_basco)
Josh Pack - Senior Prime Trader, Coinbase Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
May 26, 202625 min
Fed Hawkishness, Nvidia Earnings Implications, and Tokenization Risks
We cover how the April Fed minutes challenged the one-way cut narrative, why Nvidia’s strong earnings and the broader AI CapEx cycle are supporting equities without necessarily lifting crypto, and how bitcoin has absorbed meaningful ETF outflows without breaking down. We also discuss the latest roadblock for tokenized equities.
Main sections
(01:25 - 06:50) Fed minutes and rates repricing
(06:50 - 13:50) Nvidia earnings implications and equity resilience
(13:50 - 19:08) Bitcoin ETF outflows and absorption
(19:08 - 24:26) Tokenized equities and regulatory concerns
Speakers
Colin Basco - Quantitative Strategist, Coinbase (X: https://x.com/colin_basco)
Josh Pack - Senior Trader, Prime Trading Desk Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
May 20, 202640 min
Hyperliquid x Coinbase, Solana’s Alpenglow, and Bitcoin's Key Indicators (ft. Lark Davis)
we sit down with Lark Davis to discuss why hotter inflation data is forcing markets to rethink the Fed’s room to cut, and why that may keep crypto in a more selective regime. We cover whether Bitcoin is really an inflation hedge, why BTC dominance may stay elevated if liquidity remains tight, and how traders are weighing onchain data, technicals, and institutional ETF flows. We also discuss Solana’s Alpenglow upgrade and why better technology still needs to translate into usage and token value capture. We finish by analyzing the new Hyperliquid x Coinbase partnership and why Hyperliquid remains one of crypto’s clearest product-market-fit stories.Main sections:
(01:21 - 10:17) Inflation, Fed policy, and Bitcoin dominance
(10:17 - 22:21) Bitcoin key trading indicators
(22:21 - 29:20) Solana’s Alpenglow upgrade and implications
(29:20 - 39:28) Hyperliquid x Coinbase
Speakers:
Colin Basco – Quantitative Strategist, Coinbase (X: https://x.com/colin_basco)
Lark Davis – Host of The Lark Davis Show (X: https://x.com/LarkDavis) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
May 12, 202633 min
Circle’s ARC Token, Bitcoin’s CPI Test, and ETH's Staking Queue
In this episode, we focus on three of the biggest crypto stories of the week: Circle’s Q1 results and ARC token announcement, Bitcoin’s more nuanced setup after strong ETF demand ran into a hotter CPI print, and Ethereum’s increasingly important staking and float dynamics.
Main sections
(01:21 - 10:17) Circle’s Q1 results & ARC token
(10:17 - 19:16) Bitcoin after CPI
(19:16 - 23:12) The macro framework for crypto
(23:12 - 32:18) Ethereum’s setup
Speakers
Colin Basco — Quantitative Strategist (X: https://x.com/colin_basco)
Greg Sutton — Head of Prime Trading Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
April 28, 202632 min
AI Risks in DeFi, the Rise of Prediction Markets, and Bitcoin’s Critical Test
We connect the week’s biggest macro and crypto stories, from Iran-driven oil volatility and the equities earnings backdrop to bitcoin’s increasingly important test near $80K. We discuss why rising spot ETF inflows and tighter float have made BTC’s rebound more meaningful, but not yet a confirmed regime shift, and why the short-term holder cost basis remains the key level to watch. We also examine the fallout from the Kelp DAO exploit, how AI may increase risk in DeFi, and why prediction markets have evolved from a niche crypto product into a multi-billion-dollar industry driven by sports, geopolitics, and changing user behavior.
Main sections:
(04:31 - 12:21) The macro setup
(12:21 - 20:25) Bitcoin’s rebound and key levels
(20:43 - 27:36) DeFi’s security problem and Mythos AI Implications
(27:36 - 34:38) Prediction markets
Speakers
David Duong, CFA - Global Head of Investment Research (X: https://x.com/DavidDuong)
Colin Basco - Research Associate (X: https://x.com/colin_basco) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
April 21, 202642 min
Introducing the Coinbase Advanced Podcast
In this inaugural episode of the Coinbase Advanced podcast, we break down one of the most confusing macro environments in modern history as crypto sentiment snaps back amid Middle East negotiations. The conversation explores the blurring lines between risk-on and risk-off assets, the systemic security threats posed by Anthropic’s new Mythos AI model, and recent DeFi contagion events involving Kelp DAO and Aave. We also dive into the evolution of the "Everything Exchange," examining how the introduction of 24/7 equity perpetuals, commodities trading, and institutional bitcoin accumulation are fundamentally altering the market structure for active traders.
(00:00 - 04:38) Coinbase introduces its new monthly series for advanced traders alongside a look at shifting macro sentiment and the SEC’s new podcast.
(04:38 - 09:07) Scott Melker discusses the breakdown of traditional "risk-off" assets and why current market conditions are the most confusing in history.
(09:07 - 15:02) The team analyzes the security risks of Anthropic’s Mythos AI model and recent DeFi exploits that highlight the danger of "unknown unknowns" in smart contracts.
(15:02 - 17:24) Moheeth breaks down Coinbase Advanced data showing a surge in spot volume and a widening base of unique active traders.
(17:24 - 21:07) A deep dive into bitcoin accumulation trends, institutional "strong hands" taking over retail supply, and the significance of whale wallet movements.
(21:07 - 31:21) The conversation shifts to the growth of derivatives, including USDC open interest rewards and the transition of Coinbase into a full-stack trading venue.
(31:21 - 37:32) Scott and Moheeth explore the disruptive potential of 24/7 equity perpetuals and how 100x leverage on everything will gamify global markets.
(37:32 - 41:17) The episode concludes with a look at diversifying trade flows into altcoins and commodities like gold and silver as traders seek an edge in volatile markets.
Speakers:
David Duong, CFA — Global Head of Investment Research (X: DavidDuong)
Moheeth Alvi — Product Lead, Coinbase Advanced (X: @MoheethR)
Scott Melker — The Wolf of Wall Street (X: scottmelker)Additional disclaimer:Listed futures and swaps are offered via Coinbase Financial Markets (“CFM”). CFM is a Futures Commission Merchant (FCM) registered with the National Futures Association (NFA), and regulated by the Commodity Futures Trading Commission (CFTC). Our offerings are available only to US residents. Trading in futures and options involves substantial risks. You should only trade in financial products that you are familiar with and understand the associated risks, and after carefully considering whether such trading is suitable in light of your investment experience, financial position, and investment objectives.Please note, not all products, such as equity perpetual contracts would be available to customers in all jurisdictions. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
April 14, 202634 min
The Fed's Double Bind, Bitcoin's Outperformance, Hyperliquid's Edge, and Bittensor’s Governance Shock
We unpack why oil remains the key macro lens for understanding markets as renewed Iran diplomacy, elevated crude prices, stronger labor data, and sticky inflation risks continue to shape the Fed backdrop and broader risk sentiment. We discuss why Bitcoin has remained relatively resilient in this environment and how we are thinking about the market in a headline-driven regime where tactical levels matter more than long-term conviction. We also break down why Strategy’s bitcoin purchases may still matter even if they look small in aggregated flow data, particularly through momentum, liquidity, and float absorption. Finally, we explore why Hyperliquid continues to strengthen its case as a weekend macro price discovery venue through oil and precious metals perps, and why Covenant’s exit from Bittensor has become a real near-term sentiment hit for TAO without necessarily invalidating the broader decentralized AI thesis.Main sections
(00:41 - 07:43) The macro setup
(07:43 - 16:18) Bitcoin, oil, and market structure
(16:25 - 27:01) Strategy’s bitcoin buying & implications
(27:01 - 29:35) Hyperliquid’s competitive edge
(29:35 - 33:06) Bittensor and Covenant's exit
Speakers
David Duong, CFA - Global Head of Investment Research (X: https://x.com/DavidDuong)
Colin Basco - Research Associate (X: https://x.com/colin_basco) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
April 1, 202644 min
AI Agents, Ethereum’s Comeback, and Crypto-Backed Mortgages
We unpack the latest cross asset price action in response to surging oil prices and what elevated energy prices could mean for inflation, the Fed, and broader risk sentiment. We then explore why AI agents may become one of the most important structural themes in crypto, as autonomous software increasingly needs wallets, payments, settlement, and coordination rails to transact at scale. We also discuss Ethereum’s evolving institutional story, including why activity and liquidity may be re-centering around Ethereum L1 as the fee gap versus L2s narrows and upcoming upgrades improve the base layer’s execution capacity. Finally, we look at crypto’s deeper move into household finance through products like crypto-backed mortgages and 401(k) access, and why that could mark an important next phase in the asset class’s institutionalization.
Key sections:
(00:00 - 14:07) Iran, oil, and the macro backdrop: why the breakout above $100 in crude oil futures matters, how elevated energy prices are tightening financial conditions, and implications for risk assets.
(14:07 - 20:08) Why AI agents matter for crypto: how the narrative has shifted from model training to inference, reasoning, and persistent agents, and why autonomous software may need crypto-native payments, wallets, and settlement rails to function as real economic actors.
(20:08 - 27:48) Where value may accrue in the AI-agent stack: foundational rails, coordination layers, and integrity layers, plus how x402, Base, and tokens tied to agent coordination or decentralized intelligence fit into that framework.
(27:48 - 37:43) Ethereum’s institutional moment and the L1/L2 narrative shift: why lower mainnet fees and upcoming upgrades may be helping activity, liquidity, stablecoins, and tokenized assets re-center around Ethereum L1.
(37:43 - 42:17) Crypto-backed mortgages and 401(k)s: why crypto’s integration into core household financial products could be a meaningful next step for institutional adoption, even if the long-term structure still depends on greater regulatory clarity.Speakers:
David Duong, CFA - Global Head of Investment Research (X: DavidDuong)
Colin Basco - Research Associate (X: colin_basco)
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
March 25, 202628 min
A New Crypto Taxonomy, Ethereum’s Supply Sink, and Tokenizing the S&P 500
In this episode, we step back from the macro noise and focus on the biggest crypto stories of the week:
(03:11 - 05:18) Why tokenization, stablecoins, AI agents, and onchain commerce are emerging as core crypto infrastructure themes. Plus, Coinbase Asset Management’s tokenized bitcoin yield fund on Base and what it says about institutional demand for compliant onchain products.
(05:18 - 08:51) Why Hyperliquid’s launch of an S&P 500 perpetual matters beyond a single product: the significance of securing an official S&P license, why this helps validate Hyperliquid as more than a crypto-only venue, and how it could set a precedent for more licensed benchmark exposure to move onchain.
(08:51 - 18:58) Breaking down the new SEC-CFTC digital commodity taxonomy: how it reduces legal ambiguity, why that matters for institutional allocation, and why it may benefit altcoins
(18:58 - 26:21) Ethereum’s emerging supply sink: why BlackRock’s staked ETH ETF changes the demand story, how staking and treasury holdings are reducing ETH’s tradable float, and why that could become increasingly important for Ethereum’s long-run supply-demand profileSpeakers:
David Duong, CFA - Global Head of Investment Research (X: DavidDuong)
Colin Basco - Research Associate (X: colin_basco)
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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